JANX007

Drug

Drug Profile

JANX007 is Janux Therapeutics' investigational PSMA-directed TRACTr immunotherapy candidate for metastatic castration-resistant prostate cancer. It is in ongoing Phase 1 development with reported interim efficacy and manageable cytokine release syndrome profile, including exploration of every-two-week dosing and earlier-line settings. The drug remains investigational.

Drug Class
PSMA-directed TRACTr T-cell engager immunotherapy
Approval Status
Investigational; in Phase 1 clinical development
Mechanism of Action
Tumor-activated T-cell engager targeting PSMA to activate anti-tumor T-cell killing in prostate cancer
Brand Names
  • JANX007
Indications
  • \Metastatic castration-resistant prostate cancer (mCRPC)\

Related News

Related Clinical Trials

NCT ID Title Status Phase
NCT05519449

Study of JANX007 in Subjects With Metastatic Castration-Resistant Prostate Cancer (ENGAGER-PSMA-01)

RECRUITING PHASE1