NCT07347990 Safety and Efficacy of Iptacopan in Patients With High-Risk Transplantation-Associated Thrombotic Microangiopathy Status NOT_YET_RECRUITING Phase NA
NCT06994845 Study to Assess the Efficacy, Pharmacokinetics, Safety and Tolerability of Iptacopan in Pediatric Patients With Primary IgAN Status RECRUITING Phase PHASE3
NCT06903234 Post-authorization Safety Study of Iptacopan in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Using Data From the IPIG PNH Registry Status ACTIVE_NOT_RECRUITING Phase N/A
NCT06847607 A Multicenter Prospective Study of Iptacopan in the Treatment of Refractory/Relapsed Autoimmune Hemolytic Anemia (AIHA) Status NOT_YET_RECRUITING Phase NA
NCT06797518 Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN Status RECRUITING Phase PHASE2
NCT06517758 A Phase III Study to Investigate Efficacy, Safety and Tolerability of Iptacopan Compared With Placebo in Participants Aged 18 to 85 Years With gMG. Status RECRUITING Phase PHASE3
NCT06388941 Iptacopan in Patients With ANCA Associated Vasculitis Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05935215 Efficacy and Safety of Switching From Anti-C5 Antibody Treatment to Iptacopan Treatment in Study Participants With Atypical Hemolytic Uremic Syndrome (aHUS) Status RECRUITING Phase PHASE3
NCT05755386 Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN Status RECRUITING Phase PHASE3
NCT05630001 Single Arm, Open Label Trial With Iptacopan Treatment for 24 Weeks, in Patients on Stable Regimen of Anti-C5 Who Switch to Iptacopan. Status COMPLETED Phase PHASE3
NCT05086744 Basket Study to Assess Efficacy, Safety and PK of Iptacopan (LNP023) in Autoimmune Benign Hematological Disorders Status TERMINATED Phase PHASE2
NCT05078580 Pharmacokinetic (PK) and Safety Study of Iptacopan (LNP023) in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Matched Control Healthy Participants With Normal Hepatic Function. Status COMPLETED Phase PHASE1
NCT04889430 Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy Status COMPLETED Phase PHASE3
NCT04817618 Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy. Status RECRUITING Phase PHASE3
NCT04747613 Long-term Safety and Tolerability of Iptacopan in Patients With Paroxysmal Nocturnal Hemoglobinuria Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT03439839 Study of Safety, Efficacy, Tolerability, Pharmacokinetics and Pharmacodynamics of LNP023 in in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Status COMPLETED Phase PHASE2