Also known as: IVIG
Three FcRn inhibitors are approved for generalized myasthenia gravis, with a head-to-head trial of efgartigimod and nipocalimab underway. Emerging therapies including telitacicept, gefurulimab, and CAR-T cell therapy (KYV-101) show promise, while Immunovant's batoclimab failed TED trials.
The FDA has accepted Hansa Biopharma's Biologics License Application for imlifidase, a desensitization treatment for highly sensitized adult kidney transplant patients with positive crossmatch against deceased donors, with a PDUFA date of December 19, 2026.
CAR T-cell therapy is delivering high remission rates for multiple myeloma patients, with improved handoff communication reducing infection risks. FDA-approved BCMA-targeting products show response rates from 72% to 98% in heavily pretreated patients.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07561125 |
Effects of IVIG for BPD in Preterm Infant Born at 28 Weeks and Below |
RECRUITING | PHASE2 |
| NCT07202052 |
Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Platform Trial (RATIONAL-PT) |
RECRUITING | PHASE2/PHASE3 |
| NCT06925360 |
IVIG Trial for the Treatment of Bronchopulmonary Dysplasia |
RECRUITING | PHASE2 |
| NCT06183008 |
IVIG in Painful Sensory Neuropathy |
NOT_YET_RECRUITING | PHASE4 |
| NCT05634824 |
IVIg Plus Low Dose rhTPO for ITP in Pregnancy |
UNKNOWN | PHASE2 |
| NCT05604859 |
Evaluate the Efficacy and Safety of Various Treatment Schemes for Severe Fever With Thrombocytopenia Syndrome(SFTS) |
UNKNOWN | PHASE4 |
| NCT05520892 |
Two Regimens of IVIG in the Treatment of Newly Diagnosed ITP in Children |
RECRUITING | PHASE4 |
| NCT05134792 |
Effect of Pre-emptive Intravenous Immunoglobulin (IVIG) on the Incidence of Septic Episodes in Pediatric Burn Patients |
COMPLETED | PHASE2/PHASE3 |
| NCT05114941 |
Comparison of the Efficacy and Safety of Immunoadsorption and Intravenous Immunoglobulin for Guillain-Barre Syndrome |
NOT_YET_RECRUITING | NA |
| NCT05104762 |
IVIG Versus Plasmapheresis in the Treatment of Guillian Barrie Syndrome Patients |
COMPLETED | PHASE2/PHASE3 |
