NCT05867251 Study of AVZO-021 in Patients With Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT05806671 Dalpiciclib Plus Fulvestrant With Pyrotinib in Hormone Receptor-positive, HER2-low Advanced Breast Cancer That Progressed on Previous CDK4/6i Plus AI Therapy Status NOT_YET_RECRUITING Phase PHASE2
NCT05768139 First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT05759949 First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors Status COMPLETED Phase PHASE1
NCT05735080 Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer Status RECRUITING Phase PHASE1/PHASE2
NCT05720260 Immunotherapy, Hormone Therapy, and AKT Inhibitor for Premenopausal ER Positive MBC Status RECRUITING Phase PHASE2
NCT05683418 A Study to Evaluate the Safety and Tolerability of TOS-358 in Women With HR+ HER2- Breast Cancer Status RECRUITING Phase PHASE1
NCT05654623 A Study to Learn About a New Medicine Called Vepdegestrant (ARV-471, PF-07850327) in People Who Have Advanced Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05646862 A Study Evaluating the Efficacy and Safety of Inavolisib Plus Fulvestrant Compared With Alpelisib Plus Fulvestrant in Participants With HR-Positive, HER2-Negative, PIK3CA Mutated, Locally Advanced or Metastatic Breast Cancer Post CDK4/6i and Endocrine Combination Therapy Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05631795 Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatment Status COMPLETED Phase PHASE4
NCT05601440 Liquid-biopsy Informed Platform Trial to Evaluate CDK4/6-inhibitor Resistant ER+/HER2- Metastatic Breast Cancer Status RECRUITING Phase PHASE2
NCT05577923 Exploring Whether Disease-free Intervals Can Guide Endocrine Combined Targeted Therapy for ER+/HER2+ Advanced Breast Cancer (T-sunflower) Status NOT_YET_RECRUITING Phase PHASE2
NCT05574881 Dalpiciclib, Fulvestrant, Trastuzumab and Pertuzumab in HR Positive, HER2 Positive Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT05573126 Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer Status RECRUITING Phase PHASE1/PHASE2
NCT05564377 Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial Status RECRUITING Phase PHASE2
NCT05554354 Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial) Status TERMINATED Phase PHASE2
NCT05536128 Evaluating the Efficacy and Safety of Fulvestrant Plus DNA Damage Repair Inhibitors After a CDK4/6 Inhibitor Status RECRUITING Phase PHASE2
NCT05524584 Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer Status RECRUITING Phase PHASE2
NCT05501886 Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1) Status ACTIVE_NOT_RECRUITING Phase PHASE3