News Related to Entresto (Sacubitril/Valsartan)

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Novartis Q2 2026: Entresto Sales Plunge 50%, Pipeline Advances, and Plant Closure

Jul 21, 2026

Novartis posted Q2 2026 earnings above expectations but a 50% drop in Entresto sales from U.S. generics hurt performance. The company highlighted new EU and Japan approvals for Rhapsido and Itvisma, and a manufacturing restructuring including a German plant closure and investment in radioligand production. A $1.8 billion peptide drug pact with Unnatural Products was also announced.