NCT07730151 Efficacy and Safety of Darolutamide Combined With Docetaxel and ADT as Neoadjuvant Therapy for Locally Advanced Prostate Cancer. Status NOT_YET_RECRUITING Phase PHASE2
NCT07723248 A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1) Status RECRUITING Phase PHASE3
NCT07711002 Saruparib in Combination With Physician's Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05) Status NOT_YET_RECRUITING Phase PHASE3
NCT07620041 QLC5508 in Advanced Solid Tumors:: C-QTc, Pharmacokinetics (PK) Comparisons and Drug-drug Interaction Status NOT_YET_RECRUITING Phase PHASE1
NCT07617272 Prostate Androgen Response Investigation Using a Stratification BIOmarker; Predicting Prostate Cancer Downstaging by Neoadjuvant Darolutamide With PCAI ImmunoScore Status RECRUITING Phase PHASE2
NCT07611110 AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01) Status RECRUITING Phase PHASE3
NCT07538843 An Observational Study Conducted in China to Evaluate the Efficacy and Safety of Darolutamide in Combination With Androgen Deprivation Therapy (ADT) for Men With Non-metastatic Prostate Cancer That Progressed Following Prior Bicalutamide + ADT Treatment Status RECRUITING Phase N/A
NCT07476677 Darolutamide ± ADT as Neoadjuvant Therapy in High-Risk/Very High-Risk Localized Prostate Cancer Status NOT_YET_RECRUITING Phase PHASE2
NCT07450599 A Study to Learn How Well a Combination of Darolutamide and Androgen Deprivation Therapy (ADT) Works as a Treatment Before Surgery for Men Who Have High-risk Localized Prostate Cancer. Status RECRUITING Phase PHASE2
NCT07428642 PSMA PET/CT-Based Multimodal Model for Predicting Response to First-Line Therapy in mHSPC. Status COMPLETED Phase N/A
NCT07406282 A Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology Clinics Status RECRUITING Phase N/A
NCT07244341 A Study of Valemetostat (DS-3201b) in Combination With Darolutamide in Metastatic Castration Resistant Prostate Cancer (mCRPC) Status RECRUITING Phase PHASE1
NCT07190300 TulmiSTAR-02: A Phase I/II Open-label Study of Tulmimetostat in Combination With Darolutamide vs. Darolutamide, and Tulmimetostat With Abiraterone in Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC) Status RECRUITING Phase PHASE1/PHASE2
NCT07142551 Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response Status RECRUITING Phase PHASE2
NCT07140900 Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer Status RECRUITING Phase PHASE1
NCT07027124 Neoadjuvant ADT + Darolutamide With Pembrolizumab, Followed by Adjuvant Pembrolizumab in Molecularly Stratified High-Risk Prostate Cancer Status RECRUITING Phase PHASE2
NCT07016399 Neoadjuvant Darolutamide Alone or in Combination With Standard Therapy for Stage II-IIIA, AR+, TNBC Status RECRUITING Phase PHASE2
NCT06724159 Observational Study of the Effectiveness of Funded Drugs for Genitourinary Tumors. Status RECRUITING Phase N/A
NCT06660862 Evaluating Treatment Outcomes Using Darolutamide and Androgen Deprivation Therapy in Patients With Metastatic Hormone-Sensitive Prostate Cancer. Status NOT_YET_RECRUITING Phase PHASE4
NCT06631521 Neoadjuvant Darolutamide and Relugolix Combination Preceding Radical Prostatectomy for Prostate Cancer Status RECRUITING Phase PHASE1