NCT06977711 Loncastuximab and Roflumilast Added to R-CHOP (Lo-(Rituximab and Roflumilast) RR-CHOP) for Naïve High-Risk Diffuse Large B-cell Lymphoma (DLBCL) Status RECRUITING Phase PHASE1
NCT06968195 Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma Status SUSPENDED Phase PHASE1
NCT06966700 A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032) Status RECRUITING Phase PHASE3
NCT06961786 TNFα and IL-2 Coding Oncolytic Adenovirus TILT-123 With Lymphocyte-depleting Chemotherapy and TILs in the Treatment of Melanoma Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT06961357 Clinical Trial of CD40L-augmented TIL for Patients With Advanced Melanoma Status RECRUITING Phase PHASE1/PHASE2
NCT06959537 A Phase Ib Study of Novel Combination (New) of Low Dose Oral CyclophoSphamide (s) to Potentiate Axatilimab (A) + Retifanlimab (R) in Treating Metastatic Triple Negative Breast Cancer (TNBC) Status RECRUITING Phase PHASE1
NCT06954805 Defining ctDNA Metrics in Posttransplant Lymphoproliferative Disorder (PTLD) Status RECRUITING Phase PHASE2
NCT06942039 Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation Status RECRUITING Phase EARLY_PHASE1
NCT06940297 Dasatinib and Quercetin With CAR-T Therapy for the Treatment of Patients With Relapsed or Refractory Multiple Myeloma Status RECRUITING Phase PHASE2
NCT06939270 CD73/AXL Targeted HypoSti.CAR-T Cells in CD73/AXL Positive Advanced/Metastatic Solid Tumors Status NOT_YET_RECRUITING Phase PHASE1/PHASE2
NCT06930651 A Phase I/II Study of CAR.70-Engineered IL15-Transduced Cord Blood-Derived NK Cells With TGF-beta Receptor 2 (TGFBR2) Knock Out in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Myeloid Malignancies Status RECRUITING Phase PHASE1/PHASE2
NCT06918431 Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Status RECRUITING Phase PHASE2
NCT06916767 Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma Status RECRUITING Phase PHASE1
NCT06911502 A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4) Status RECRUITING Phase PHASE3
NCT06904066 Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies Status RECRUITING Phase PHASE1
NCT06898385 A Phase I Clinical Study of IX001 TCR-T Injection in the Treatment of Advanced Pancreatic Cancer Patients With KRAS G12V Mutation Status RECRUITING Phase PHASE1
NCT06897930 A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE Status RECRUITING Phase PHASE1/PHASE2
NCT06890884 A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011) Status RECRUITING Phase PHASE2
NCT06885697 Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma Status RECRUITING Phase PHASE1