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Ceftriaxone

Ceftriaxone

Drug

Drug Profile

Ceftriaxone is a third-generation cephalosporin antibiotic used to treat a wide range of bacterial infections including pneumonia, meningitis, urinary tract infections, gonorrhea, and sepsis. It is administered intravenously or intramuscularly. It is a widely used prescription antibacterial medicine.

Drug Class: Third-generation cephalosporin antibiotic
Approval Status: Approved for medical use in 1982; prescription-only in the US
Mechanism of Action: Prevents bacteria from making a cell wall

Brand Names

Rocephin
Epicephin
Wintriaxone

Indications

\Middle ear infections\
Endocarditis
Meningitis
Pneumonia
\Bone and joint infections\
\Intra-abdominal infections\
\Skin infections\
\Urinary tract infections\
Gonorrhea
\Pelvic inflammatory disease\
\Bacterial sepsis\

Related News

CDC Investigates First U.S. Outbreak of XDR Salmonella with NDM-1 Gene Linked to Moringa Capsules

Feb 14, 2026

The CDC is investigating a multistate outbreak of extensively drug-resistant Salmonella Newport with an NDM-1 gene linked to Rosabella moringa powder capsules, marking the first documented outbreak of Salmonella with an NDM-1 gene in the United States.

Extensively Drug-Resistant Salmonella Outbreak Linked to Rosabella Moringa Capsules

Feb 13, 2026

CDC and FDA are investigating a multistate outbreak of extensively drug-resistant Salmonella Newport infections linked to Rosabella brand moringa powder capsules, with seven people sickened across seven states and three requiring hospitalization.

Related Clinical Trials

NCT ID	Title	Status	Phase
NCT06828952	Risk Factors of Failure of Conservative Treatment in Acute Non Complicated Appendicitis	NOT_YET_RECRUITING
NCT06349122	Screen-and-treat Strategy for Vaginal Flora Abnormalities in Pregnant Women at High Risk of Preterm Birth	NOT_YET_RECRUITING	PHASE4
NCT05980871	Treatment Responses of Early Syphilis to Ceftriaxone Plus Doxycycline	TERMINATED	PHASE4
NCT05971550	Clearance of Asymptomatic Pharyngeal Carriage of Neisseria Gonorrhoeae With or Without Ceftriaxone Treatment: Randomized Non-inferiority Study	NOT_YET_RECRUITING	PHASE3
NCT05470517	Antibiotic Instillation in Appendicitis	COMPLETED	PHASE2
NCT05375240	Propranolol on Post Stroke Immune Status and Infection	UNKNOWN	PHASE2
NCT05294588	Efficacy of Immunization With 4C-MenB in Preventing Experimental Urethral Infection With Neisseria Gonorrhoeae	COMPLETED	PHASE2
NCT05149287	PROPER Trial of Pain and Inflammation After Knee Arthroscopy	TERMINATED	PHASE2
NCT05079620	Early Antibiotics After Aspiration in ICU Patients	TERMINATED	PHASE4
NCT04870138	Experimental Human Infection With Neisseria Gonorrhoeae (LptA Trial)	COMPLETED	PHASE1