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NCT04924075 Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015) Status RECRUITING Phase PHASE2
NCT04846920 A Study of Belzutifan (MK-6482) in Participants With Advanced Clear Cell Renal Cell Carcinoma (MK-6482-018) Status COMPLETED Phase PHASE1
NCT04736706 A Study of Pembrolizumab (MK-3475) in Combination With Belzutifan (MK-6482) and Lenvatinib (MK-7902), or Pembrolizumab/Quavonlimab (MK-1308A) in Combination With Lenvatinib, Versus Pembrolizumab and Lenvatinib, for Treatment of Advanced Clear Cell Renal Cell Carcinoma (MK-6482-012) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04626518 Substudy 03B: A Study of Immune and Targeted Combination Therapies in Participants With Second Line Plus (2L+) Renal Cell Carcinoma (MK-3475-03B/KEYMAKER-U03) Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04626479 Substudy 03A: A Study of Immune and Targeted Combination Therapies in Participants With First Line (1L) Renal Cell Carcinoma (MK-3475-03A) Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04586231 A Study of Belzutifan (MK-6482) in Combination With Lenvatinib Versus Cabozantinib for Treatment of Renal Cell Carcinoma (MK-6482-011) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04489771 A Study of Belzutifan (MK-6482) in Participants With Advanced Renal Cell Carcinoma (MK-6482-013) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04195750 A Study of Belzutifan (MK-6482) Versus Everolimus in Participants With Advanced Renal Cell Carcinoma (MK-6482-005) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT03634540 A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT03445169 A Food Effect Study in Healthy Volunteers With Belzutifan (PT2977, MK-6482) Tablets Status COMPLETED Phase PHASE1
NCT03401788 A Phase 2 Study of Belzutifan (PT2977, MK-6482) for the Treatment of Von Hippel Lindau (VHL) Disease-Associated Renal Cell Carcinoma (RCC) (MK-6482-004) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT02974738 A Trial of Belzutifan (PT2977, MK-6482) Tablets In Patients With Advanced Solid Tumors (MK-6482-001) Status ACTIVE_NOT_RECRUITING Phase PHASE1