SLAS Technology Volume 37 Highlights AI Drug Design and Field-Ready Diagnostics
Volume 37 of SLAS Technology features an AI drug discovery framework, a pipelining Bayesian optimization method, and a field-deployable virus detection platform.
Ampicillin
DrugDrug Profile
Ampicillin is an aminopenicillin antibiotic used to prevent and treat multiple bacterial infections, including respiratory, urinary, meningeal, and endocardial infections. It is available in oral and injectable forms and is widely used in clinical practice. The drug came into commercial use in the early 1960s and is prescription-only in the U.S.
- Drug Class
- Aminopenicillin antibiotic
- Approval Status
- Commercially introduced in 1961; prescription-only in the US
- Mechanism of Action
- Beta-lactam antibacterial action against susceptible gram-positive and gram-negative bacteria
- Principen
- \Respiratory tract infections\
- \Urinary tract infections\
- Meningitis
- Salmonellosis
- Endocarditis
Related News
Antimicrobial Resistance in Foodborne Bacteria Remains High Across Europe
A joint report from the European Food Safety Authority and the European Centre for Disease Prevention and Control finds antimicrobial resistance in Salmonella and Campylobacter continues to pose a public health concern across Europe, though several countries have reported progress in reducing resistance levels.
CDC Investigates First U.S. Outbreak of XDR Salmonella with NDM-1 Gene Linked to Moringa Capsules
The CDC is investigating a multistate outbreak of extensively drug-resistant Salmonella Newport with an NDM-1 gene linked to Rosabella moringa powder capsules, marking the first documented outbreak of Salmonella with an NDM-1 gene in the United States.
Extensively Drug-Resistant Salmonella Outbreak Linked to Rosabella Moringa Capsules
CDC and FDA are investigating a multistate outbreak of extensively drug-resistant Salmonella Newport infections linked to Rosabella brand moringa powder capsules, with seven people sickened across seven states and three requiring hospitalization.
Related Clinical Trials
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07563504 |
PROMab Trial: Ampicillin With or Without Gentamicin for Term Prelabour Rupture of Membranes |
NOT_YET_RECRUITING | PHASE4 |
| NCT06368102 |
Prophylactic Effects for Preventing Surgical Site Infection in Third Molar Surgery |
COMPLETED | PHASE4 |
| NCT05977400 |
NICU Antibiotics and Outcomes (NANO) Follow-up Study |
NOT_YET_RECRUITING | PHASE3 |
| NCT05051163 |
Strategies to Reduce Mortality Among HIV-infected and HIV-exposed Children Admitted With Severe Acute Malnutrition |
UNKNOWN | PHASE2/PHASE3 |
| NCT04202380 |
Azithromycin for Preterm Pre-labor Rupture of Membranes |
COMPLETED | NA |
| NCT04041791 |
A Study to Compare Different Antibiotics and Different Modes of Fluid Treatment for Children With Severe Pneumonia |
COMPLETED | PHASE3 |
| NCT03997266 |
NICU Antibiotics and Outcomes Trial |
COMPLETED | PHASE4 |
| NCT03060473 |
Treatment of ppROM With Erythromycin vs. Azithromycin Trial |
TERMINATED | PHASE3 |
| NCT02477423 |
A Randomized Controlled Trial Investigating if Antibiotic Use in the First 48 Hours of Life Adversely Impacts the Preterm Infant Microbiome |
COMPLETED | NA |
| NCT02427932 |
Pharmacokinetic (PK) and Pharmacodynamic (PD) Modeling of Ampicillin and Gentamicin in Peripartum Patients |
COMPLETED |