Amoxicillin clavulanic acid

Drug

Drug Profile

Amoxicillin clavulanic acid (co-amoxiclav) is a combination antibiotic medicine marketed under brands such as Augmentin. It combines amoxicillin with clavulanate to treat a broad range of bacterial infections, including respiratory, skin, urinary, and bite-related infections. It has been approved for medical use in the United States since 1984.

Drug Class
Combination antibiotic (beta-lactam antibiotic + beta-lactamase inhibitor)
Approval Status
Approved for medical use in the United States in 1984; prescription-only
Mechanism of Action
Amoxicillin provides antibacterial penicillin activity, while clavulanic acid inhibits beta-lactamase to protect amoxicillin from enzymatic inactivation
Brand Names
  • Augmentin
Indications
  • \Otitis media\
  • \Streptococcal pharyngitis\
  • Pneumonia
  • Cellulitis
  • \Urinary tract infections\
  • \Animal bites\

Related News

Related Clinical Trials

NCT ID Title Status Phase
NCT07202052

Role of Antibiotic Therapy or Immunoglobulin On iNfections in hAematoLogy Platform Trial (RATIONAL-PT)

RECRUITING PHASE2/PHASE3
NCT06709196

Clinical Trial Testing Whether Targeted Antibiotic Prophylaxis Can Reduce Infections After Cystectomy Compared to Empiric Prophylaxis

RECRUITING PHASE4
NCT05079620

Early Antibiotics After Aspiration in ICU Patients

TERMINATED PHASE4
NCT01015417

Place of Antibiotics in the Postoperative Acute Lithiasic Cholecystitis

COMPLETED PHASE3
NCT00656747

Moxifloxacin Versus Amoxicillin Clavulanic Acid in Treatment of Acute Exacerbation of Chronic Bronchitis

COMPLETED PHASE4