Nicox SA received positive written feedback from a pre-NDA meeting with the FDA for NCX 470, a nitric oxide-donating bimatoprost eye drop for glaucoma. The NDA submission remains on track for summer 2026.
Ocular Therapeutix announced positive topline results from SOL-1, its Phase 3 superiority trial of AXPAXLI for wet age-related macular degeneration, meeting primary and durability endpoints with high statistical significance.
Recent studies demonstrate tirzepatide's efficacy extends beyond diabetes management, showing reduced glaucoma risk in diabetic patients and significant improvements in pediatric Type 2 diabetes treatment with superior weight loss outcomes.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07588152 |
Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular Hypertension |
NOT_YET_RECRUITING | PHASE4 |
| NCT07390890 |
DSLT for Reducing Medication in Glaucoma |
RECRUITING | |
| NCT07335211 |
Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular Hypertension |
RECRUITING | PHASE3 |
| NCT07325240 |
24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients |
RECRUITING | PHASE4 |
| NCT07218796 |
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone) |
RECRUITING | PHASE3 |
| NCT07218783 |
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine) |
RECRUITING | PHASE3 |
| NCT07217678 |
Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use |
RECRUITING | PHASE4 |
| NCT07210216 |
GLAUcoma Diagnostic and Imaging Analysis (GLAUDIA) Study |
NOT_YET_RECRUITING | |
| NCT07154810 |
Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With the SpyGlass Bimatoprost Implant System / IOL Combination |
ACTIVE_NOT_RECRUITING | |
| NCT07154797 |
Evaluation of the Safety and Effectiveness of the Bimatoprost Implant System / IOL Combination in Patients With Ocular Hypertension or Mild to Moderate Open-angle Glaucoma |
COMPLETED | NA |
