News Related to Non-Cardioembolic Ischemic Stroke

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Phase 3 OCEANIC-STROKE trial shows asundexian cut recurrent ischemic stroke

Apr 20, 2026

Phase 3 OCEANIC-STROKE data showed asundexian plus antiplatelet therapy reduced recurrent ischemic stroke versus placebo. Major bleeding rates were similar between groups.

Factor XIa Inhibitor Reduces Stroke Recurrence Without Increasing Bleeding Risk in Phase 3 Trial

Mar 07, 2026

The phase 3 OCEANIC-STROKE trial of 12,327 patients showed asundexian, an oral Factor XIa inhibitor, reduced ischemic stroke recurrence by 26% when added to standard antiplatelet therapy, with no increase in major bleeding events.