New genomic studies show a practical recall-by-genotype strategy for psychiatry, shared genetic liability across psychiatric and physical conditions, and improved disease prediction using disease-history trajectories.
A meta-analysis of 68 studies found patients with mental disorders consistently showed higher brain age than healthy controls. The largest effects were seen in schizophrenia spectrum and neurocognitive disorders.
A study of nearly 70,000 children found girls exposed to SARS-CoV-2 infection in utero had a 44% increased risk of autism spectrum disorder. The research showed 3.97% of pregnant women had COVID-19 infection, with most cases occurring in the third trimester. No increased risk was observed for boys or for speech/language and motor delays overall.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
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ACTIVE_NOT_RECRUITING | |
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NOT_YET_RECRUITING | NA |
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RECRUITING | |
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NOT_YET_RECRUITING | |
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High Depth Exome Sequencing on DNA From a Salivary Sample by Mouth Smear. |
NOT_YET_RECRUITING | |
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RECRUITING | NA |
