News Related to Neurodegenerative Disorder

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TREM2 Antibody Guides Microglia Toward Protective Phenotype in Alzheimer's Disease

Mar 02, 2026

New research identifies a key microglial subpopulation regulated by anti-TREM2 antibody therapy in Alzheimer's disease, revealing how the treatment guides microglia toward protective differentiation pathways.

Ultragenyx Cuts 10% of Workforce After FDA Rejects Gene Therapy Application

Feb 13, 2026

Ultragenyx will lay off 130 employees as part of restructuring aimed at profitability by 2027. The FDA rejected the company's gene therapy application for Sanfilippo syndrome due to manufacturing concerns.