NCT04709458 Safety and Early Efficacy Study of TBX-2400 in Patients With AML or Myelofibrosis Status UNKNOWN Phase PHASE1
NCT04679870 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral GB2064 in Participants With Myelofibrosis Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04676529 Study to Evaluate Safety, Pharmacokinetic and Pharmacodynamic Dose Escalation and Expansion Study of PXS-5505 in Patients With Primary, Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis Status COMPLETED Phase PHASE1/PHASE2
NCT04655118 Study of TL-895 in Subjects With Myelofibrosis or Indolent Systemic Mastocytosis Status RECRUITING Phase PHASE2
NCT04640532 KRT-232 in Combination With TL-895 for the Treatment of R/R MF and KRT-232 for the Treatment of JAKi Intolerant MF Status UNKNOWN Phase PHASE1/PHASE2
NCT04640025 A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib Status TERMINATED Phase PHASE2
NCT04629508 To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy (LIMBER-213) Status COMPLETED Phase PHASE2
NCT04629430 Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT Status COMPLETED Phase NA
NCT04617028 Jaktinib Versus Hydroxycarbamide in Subjects With Intermediate-2 or High-risk Myelofibrosis Status COMPLETED Phase PHASE3
NCT04603495 Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04576156 A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04562870 A Study to Evaluate Single Agent Selinexor Versus Physician's Choice in Participants With Previously Treated Myelofibrosis Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04562389 Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04551066 To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313) Status TERMINATED Phase PHASE3
NCT04551053 To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304) Status TERMINATED Phase PHASE3
NCT04543279 Fostamatinib as a Single Agent or in Combination With Ruxolitinib for Treatment of Patients With Myelofibrosis With Severe Thrombocytopenia Status TERMINATED Phase PHASE2
NCT04485260 An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Ruxolitinib in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post ET-MF) Who Have a Suboptimal Response to Ruxolitinib Status UNKNOWN Phase PHASE1/PHASE2
NCT04464889 HA-1H TCR T Cell for Relapsed/Persistent Hematologic Malignancies After Allogeneic Stem Cell Transplantation Status WITHDRAWN Phase PHASE1
NCT04354727 A Study of APG-1252 in Patients With Myelofibrosis Who Progressed After Initial Therapy Status WITHDRAWN Phase PHASE1/PHASE2