NCT04640532 KRT-232 in Combination With TL-895 for the Treatment of R/R MF and KRT-232 for the Treatment of JAKi Intolerant MF Status UNKNOWN Phase PHASE1/PHASE2
NCT04640025 A Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Itacitinib Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04629508 To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy (LIMBER-213) Status COMPLETED Phase PHASE2
NCT04629430 Effects of Prebiotics on Gut Microbiome in Patients Undergoing HSCT Status COMPLETED Phase NA
NCT04617028 Jaktinib Versus Hydroxycarbamide in Subjects With Intermediate-2 or High-risk Myelofibrosis Status COMPLETED Phase PHASE3
NCT04603495 Phase 3 Study of Pelabresib (CPI-0610) in Myelofibrosis (MF) (MANIFEST-2) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04576156 A Study Comparing Imetelstat Versus Best Available Therapy for the Treatment of Intermediate-2 or High-risk Myelofibrosis (MF) Who Have Not Responded to Janus Kinase (JAK)-Inhibitor Treatment Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04562870 A Study to Evaluate Single Agent Selinexor Versus Physician's Choice in Participants With Previously Treated Myelofibrosis Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04562389 Study of Selinexor in Combination With Ruxolitinib in Myelofibrosis Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04551066 To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313) Status TERMINATED Phase PHASE3
NCT04551053 To Evaluate Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib (LIMBER-304) Status TERMINATED Phase PHASE3
NCT04543279 Fostamatinib as a Single Agent or in Combination With Ruxolitinib for Treatment of Patients With Myelofibrosis With Severe Thrombocytopenia Status TERMINATED Phase PHASE2
NCT04485260 An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 Combined With Ruxolitinib in Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post ET-MF) Who Have a Suboptimal Response to Ruxolitinib Status UNKNOWN Phase PHASE1/PHASE2
NCT04464889 HA-1H TCR T Cell for Relapsed/Persistent Hematologic Malignancies After Allogeneic Stem Cell Transplantation Status WITHDRAWN Phase PHASE1
NCT04354727 A Study of APG-1252 in Patients With Myelofibrosis Who Progressed After Initial Therapy Status WITHDRAWN Phase PHASE1/PHASE2
NCT04328844 A Study to Assess a PI3Kδ Inhibitor (IOA-244) in Patients With Metastatic Cancers Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04282421 Survival in Myelofibrosis Patients After Allogeneic Hematopoietic Stem Cell Transplantation in Five Centers in France Status COMPLETED Phase N/A
NCT04279847 Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms Status ACTIVE_NOT_RECRUITING Phase PHASE1