A pan-cancer study identified 56 local cellular programs and 13 spatial niches across 12 cancer types. Multiple niches were linked to prognosis, immunotherapy response, and macrophage spatial distribution.
Studies in muscle-invasive bladder cancer found ctDNA predicted metastatic risk after bladder-sparing treatment, while urine tumor DNA was more sensitive for residual bladder disease. Data from RETAIN-2 and a PNAS study support molecular testing to help select patients for bladder preservation.
New data from 1,868 SEER-linked patients showed DecisionDx-Melanoma identified significant five-year survival differences within the same AJCC stage. The findings were presented at the 2026 AAD Annual Meeting.
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|---|---|---|---|
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A Phase 2 Study of Luvometinib Combined With Anlotinib in KRAS-mutated NSCLC |
NOT_YET_RECRUITING | PHASE2 |
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Real-world Study of SKB264 Monotherapy or Combination Therapy in Recurrent or Metastatic HER2-negative Breast Cancer |
RECRUITING | |
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Tumor Deposits in Colorectal Cancer and Its Prognostic Value in Survival and Metastasis |
COMPLETED | |
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A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02) |
RECRUITING | PHASE1/PHASE2 |
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Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung |
RECRUITING | EARLY_PHASE1 |
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Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases |
SUSPENDED | PHASE1/PHASE2 |
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68Ga-FAPI PET/CT in Patients With Various Types of Cancer |
RECRUITING | EARLY_PHASE1 |
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Ferumoxtran-10-enhanced MRI in Prostate Cancer Patients |
TERMINATED | PHASE3 |
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Trial Evaluating the Efficacy of CARBOPLATIN in Metastatic Prostate Cancer With Gene Alterations in the Homologous Recombination Pathway |
COMPLETED | PHASE2 |
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Targeted Radiotherapy in Androgen-suppressed Prostate Cancer Patients. |
COMPLETED | NA |
