Medullary thyroid carcinoma is a neuroendocrine thyroid cancer arising from calcitonin-producing parafollicular C cells. It can be sporadic or hereditary and is biologically distinct from differentiated thyroid cancers.
GLP-1 receptor agonists like semaglutide and tirzepatide help regulate appetite and improve satiety for medical weight loss. Clinical studies show patients can lose an average of 15% of body weight with these treatments. These medications are suitable for individuals with BMI of 27+ with weight-related conditions or BMI of 30+ regardless of other conditions.
Recent studies examine safety profiles of GLP-1 receptor agonists, finding increased risk for nonscarring hair loss but improved survival in patients with brain metastases and type 2 diabetes.
GLP-1 weight loss drugs show increasing efficacy but raise concerns about excessive weight loss, side effects, and the rise of unregulated compounded versions sold online.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07383246 |
CTR-FAPI-guided Precision Surgery for Newly Diagnosed MTC |
RECRUITING | PHASE3 |
| NCT07138716 |
Research on the Application of 68Ga-DOTA-CCK-FS PET/CT in MTC |
RECRUITING | NA |
| NCT06852144 |
PET-TC in Thyroid Evaluation |
ENROLLING_BY_INVITATION | |
| NCT06520319 |
Head-to-head Study of 68Ga-MGS5 Versus 68Ga-DOTATATE PET/CT in Patients With Medullary Thyroid Carcinoma |
RECRUITING | PHASE1 |
| NCT06121271 |
Trial of Lu-177 DOTATATE (Lutathera®) in Unlicensed Indications |
NOT_YET_RECRUITING | PHASE2 |
| NCT06067594 |
Calcitonin in Needle Wash Using Electrochemiluminescence Method For Diagnosis Of Medullary Thyroid Carcinoma. |
COMPLETED | |
| NCT05534594 |
Evaluation of the 18F-PSMA Positron Emission Tomography (PET)/CT in Patients With Medullary Thyroid Cancer |
COMPLETED | NA |
| NCT04970134 |
Spanish Study for Molecular Characterization of Thyroid Carcinoma |
ACTIVE_NOT_RECRUITING | |
| NCT04787328 |
A Study of HA121-28 Tablets in Patients With Medullary Thyroid Carcinoma (MTC) |
UNKNOWN | PHASE2 |
| NCT03636945 |
Evaluation of 18F-FDOPA PET-CT in the Preoperative Initial Assessment of Medullary Thyroid Carcinoma |
UNKNOWN | NA |
