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Ketamine's Therapeutic Benefits Not Linked to Psychedelic Effects in Alcohol Use Disorder

Mar 25, 2026

New research challenges the theory that ketamine's psychedelic effects drive its therapeutic benefits for alcohol use disorder. A study of 96 participants found no link between ketamine's psychoactive experiences and improved abstinence rates. The findings suggest other mechanisms, such as brain network alterations, may explain ketamine's effectiveness in treating addiction.