Merck announced multiple data presentations at the 2026 ASCO GU Cancers Symposium, including results from trials evaluating pembrolizumab combinations in muscle-invasive bladder cancer and renal cell carcinoma.
Early trial of Rezatapopt shows 20% response rate in advanced cancers with p53 mutations, while researchers identify AMD3100 as potential solution to enable immunotherapy in rare liver cancer.
Study finds FDA-approved drug AMD3100 can mobilize immune T cells to attack fibrolamellar carcinoma, a rare liver cancer affecting children and young adults that has resisted immunotherapy treatment.
Researchers find that AMD3100, an existing FDA-approved drug, can reverse T-cell exclusion in fibrolamellar carcinoma, potentially allowing immunotherapy to fight the rare and fatal liver cancer that primarily affects children and young adults.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT06487312 |
Clinical Trial to Evaluate the Effectiveness and Safety of a Remote Automated Ultrasound Diagnostic System for Automated Ultrasound Examinations: a Prospective, Multicenter Study |
ENROLLING_BY_INVITATION | |
| NCT06364865 |
AE05ML Device for ML Hem-o-lok Polymer Clip Delivery in Laparoscopic Surgical Procedures Observational Registery Study |
COMPLETED | |
| NCT04755452 |
The Effect of Pneumoperitoneum (Raised Pressure in the Peritoneal Cavity) During Robotic Kidney/Prostate Cancer Surgery. |
COMPLETED | NA |
| NCT03634540 |
A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003) |
ACTIVE_NOT_RECRUITING | PHASE2 |
| NCT03400085 |
Pilot Study of an mHealth Intervention for Living Donor Follow-up |
ACTIVE_NOT_RECRUITING | NA |
| NCT03301987 |
Chronic Kidney Disease & Therapeutic Exercise |
COMPLETED | NA |
| NCT03090646 |
Use of Financial Incentives to Increase Live Kidney Donor Follow-up Compliance |
ACTIVE_NOT_RECRUITING | NA |
| NCT03076151 |
Pharmacokinetic Study of Adoport® (Tacrolimus) in Patients With de Novo Kidney Transplantation |
COMPLETED | PHASE4 |
| NCT02826213 |
Comparison of Two Techniques of Renal Pre-transplant Infusion on the Evolution of Renal Function in the Recipient |
COMPLETED | |
| NCT01235104 |
Impact of Total Nephrectomy on Patients With Kidney Stone |
UNKNOWN |
