Influenza A is a subtype of influenza virus that circulates in humans and contributes to seasonal epidemics; currently circulating human subtypes include A(H1N1) and A(H3N2). Type A influenza viruses are also the only influenza type known to have caused pandemics.
A 19-month-old girl with influenza A (H1N1)-associated acute necrotizing encephalitis made a complete neurological recovery despite a severity score of 6. Multimodal immunomodulatory therapy including IVIG, corticosteroids, anakinra, and plasma exchange led to rapid decline in blood cytokine levels. The case underscores early recognition and targeted treatment in young children.
New imaging reveals that most flu infections fail due to transcription errors, while host-targeted antivirals aim to bypass resistance by interfering with cellular machinery. The findings from Cell Systems point to new ways to predict viral threats and develop broad-spectrum drugs.
Two new studies reveal long COVID's lasting biological and mental health effects. A mouse study found coronavirus triggers prolonged lung and brain damage unlike influenza, while a population study linked long COVID to significantly higher depression and anxiety risks up to three years post-infection.
The CDC reported six new influenza-associated pediatric deaths in Week 6 of 2026, bringing the 2025-2026 U.S. season total to 71. About 90% of deaths with known vaccination status were in children not fully vaccinated.
Vir Biotechnology is set to report Q4 2025 earnings on Feb 23, 2026, with analysts expecting revenue of $19.91-$23.18 million and a loss of $0.41-$0.50 per share, marking a 61% year-over-year revenue increase.
Moderna announced the FDA will consider approving its mRNA-based flu vaccine for older adults after resolving a dispute over clinical trial design. The vaccine showed 34.5% higher efficacy than standard flu shots in trials.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07430410 |
Clinical Validation of an At-Home Flu A/B and COVID-19 Rapid Test |
NOT_YET_RECRUITING | NA |
| NCT07330986 |
Influenza A-associated Pulmonary Aspergillosis in Patients Admitted to the Intensive Care Unit in China |
COMPLETED | |
| NCT07314905 |
Adaptive Platform Trial of Treatments for Respiratory Infections in Community Settings (TreatResp) |
RECRUITING | PHASE3 |
| NCT07308158 |
Covid Flu A/B and RSV 4 in 1 Diagnostic Test |
COMPLETED | |
| NCT07229820 |
Efficacy and Safety of ZSP1273 in Children 12-17 Years Old With Influenza A |
ACTIVE_NOT_RECRUITING | PHASE3 |
| NCT07229807 |
Efficacy and Safety of ZSP1273 in Children 2-11 Years Old With Influenza A |
ACTIVE_NOT_RECRUITING | PHASE3 |
| NCT07217639 |
Clinical Validation of the Aptitude Medical Systems Metrix Respiratory Panel Test in At-Home/Non-Laboratory Settings |
NOT_YET_RECRUITING | NA |
| NCT07190131 |
Evaluation of COVID-19 and Flu A/B 3 in 1 Combo Rapid Test |
COMPLETED | |
| NCT07128615 |
A Phase I/II Study on Safety AND Immunogenicity of AZD4117 and AZD5315 Vaccines (PANDA) |
ACTIVE_NOT_RECRUITING | PHASE1/PHASE2 |
| NCT06800950 |
Phase III Clinical Trial of Quadrivalent Influenza Virus Split Vaccine |
NOT_YET_RECRUITING | PHASE3 |
