News Related to High-Grade Serous Ovarian Cancer

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New Studies Reveal How Cancer Cells Survive Chemotherapy and Resist Treatment

Jul 31, 2026

New studies reveal how cancer cells survive chemotherapy: fructose promotes ovarian cancer spread, platinum-treated 'zombie cells' release TGFβ in lung and ovarian cancers, and mitochondrial metabolism drives 5FU resistance in colorectal cancer. The findings point to potential combination therapy targets.

Brigatinib and Fructose: New Strategies to Overcome Ovarian Cancer Recurrence

Aug 01, 2026

Preclinical studies reveal that fructose promotes metastasis in ovarian cancer by reducing cell adhesion, while brigatinib enhances PARP inhibitor efficacy by blocking an early adaptive resistance mechanism. The findings suggest dietary modifications and repurposing a lung cancer drug could improve outcomes for high-grade serous ovarian cancer patients.