NCT04618211 Dose-ranging Study of Oral PHA-022121 for Acute Treatment of Angioedema Attacks in Patients With Hereditary Angioedema Status COMPLETED Phase PHASE2
NCT04557319 Safety and Pharmacokinetics of GNR-038 in Healthy Volunteers Status COMPLETED Phase PHASE1
NCT04349800 A Single Dose Safety, Tolerability, Pharmacokinetic and Food Effect Study of KVD900 (Sebetralstat) in Healthy Volunteers Status COMPLETED Phase PHASE1
NCT04307381 An Extension Study of Donidalorsen (IONIS-PKK-LRx) in Participants With Hereditary Angioedema Status COMPLETED Phase PHASE2
NCT04208412 A Phase II, Cross-over Clinical Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) in the On-demand Treatment of Angioedema Attacks in Adult Subjects With Hereditary Angioedema Type I or II Status COMPLETED Phase PHASE2
NCT04070326 A Study of Lanadelumab to Prevent Hereditary Angioedema (HAE) Attacks in Children Status COMPLETED Phase PHASE3
NCT04030598 A Study to Assess the Clinical Efficacy of Donidalorsen (Also Known as IONIS-PKK-LRx and ISIS 721744) in Participants With Hereditary Angioedema Status COMPLETED Phase PHASE2
NCT03712228 A Study to Investigate CSL312 in Subjects With Hereditary Angioedema (HAE) Status COMPLETED Phase PHASE2
NCT03697187 Patient Registry to Evaluate the Real-world Safety of Ruconest® Status COMPLETED Phase N/A
NCT03485911 Efficacy and Safety Study of BCX7353 as an Oral Treatment for the Prevention of Attacks in HAE Status COMPLETED Phase PHASE3
NCT03472040 A Long Term Safety Study of BCX7353 in Hereditary Angioedema Status COMPLETED Phase PHASE2/PHASE3
NCT03202784 A Relative Bioavailability Study of Two Formulations of BCX7353 Status COMPLETED Phase PHASE1
NCT03136237 A Drug-Drug Interaction Study to Evaluate Drug Transporter Interactions Status COMPLETED Phase PHASE1
NCT02854397 Determination of Specific Biomarkers of Acute Attack of Angioedema Within Pediatric Population Status TERMINATED Phase N/A
NCT02819102 An Open-label Drug-Drug Interaction Study to Evaluate the Effect of BCX7353 on Cytochrome P450 Enzyme Activity Using Probe Substrates Status COMPLETED Phase PHASE1
NCT02670720 Open-label, Long-term Safety Study of Avoralstat in Subjects With Hereditary Angioedema Status TERMINATED Phase PHASE3
NCT02448264 First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BCX7353 in Healthy Western and Japanese Volunteers Status COMPLETED Phase PHASE1