NCT04802876 Efficacy of Tislelizumab and Spartalizumab Across Multiple Cancer-types in Patients with PD1-high MRNA Expressing Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04760431 TKIs vs. Pertuzumab in HER2+ Breast Cancer Patients With Active Brain Metastases (HER2BRAIN) Status UNKNOWN Phase PHASE2
NCT04675827 De-escalation Adjuvant Chemo in HER2+/ER-/node-neg Early BC Patients Who Achieved PCR After Neoadjuvant Chemo & Dual HER2 Blockade Status TERMINATED Phase PHASE2
NCT04660929 CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04650451 Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors Status SUSPENDED Phase PHASE1
NCT04639271 Pyrotinib, Trastuzumab And Abraxane in HER2-positive MBC With Brain Metastasis Status UNKNOWN Phase PHASE2
NCT04638725 Identification of Genetic Determinants for Treatment Resistance/Sensitivity and/or Toxicity in Adjuvant Setting for HER2 Positive Breast Cancer Status RECRUITING Phase N/A
NCT04609540 Pyrotinib Combined With Trastuzumab And Chemotherapy in HER2-positive MBC Status UNKNOWN Phase N/A
NCT04605575 Pyrotinib Plus Vinorelbine in Participants With HER2-positive Previously Treated Locally Advanced or Metastatic Breast Cancer Status UNKNOWN Phase PHASE2
NCT04602117 ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer Status WITHDRAWN Phase PHASE1
NCT04588545 Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04585750 The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) Status RECRUITING Phase PHASE1/PHASE2
NCT04582968 Pyrotinib Combined With Brain Radiotherapy in Breast Cancer Patients With Brain Metastases Status UNKNOWN Phase PHASE1/PHASE2
NCT04578106 Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy Status TERMINATED Phase PHASE2
NCT04569747 A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04512261 TOPAZ: Tucatinib in COmbination With Pembrolizumab And TrastuZumab in Patients With HER2-Positive Breast Cancer Brain Metastases Status WITHDRAWN Phase PHASE1/PHASE2
NCT04487236 Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid Tumors Status COMPLETED Phase PHASE1
NCT04481932 Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer Status RECRUITING Phase PHASE2