NCT04760431 TKIs vs. Pertuzumab in HER2+ Breast Cancer Patients With Active Brain Metastases (HER2BRAIN) Status UNKNOWN Phase PHASE2
NCT04675827 De-escalation Adjuvant Chemo in HER2+/ER-/node-neg Early BC Patients Who Achieved PCR After Neoadjuvant Chemo & Dual HER2 Blockade Status TERMINATED Phase PHASE2
NCT04660929 CAR-macrophages for the Treatment of HER2 Overexpressing Solid Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04650451 Safety and Activity Study of HER2-Targeted Dual Switch CAR-T Cells (BPX-603) in Subjects With HER2-Positive Solid Tumors Status SUSPENDED Phase PHASE1
NCT04639271 Pyrotinib, Trastuzumab And Abraxane in HER2-positive MBC With Brain Metastasis Status UNKNOWN Phase PHASE2
NCT04638725 Identification of Genetic Determinants for Treatment Resistance/Sensitivity and/or Toxicity in Adjuvant Setting for HER2 Positive Breast Cancer Status RECRUITING Phase N/A
NCT04609540 Pyrotinib Combined With Trastuzumab And Chemotherapy in HER2-positive MBC Status UNKNOWN Phase N/A
NCT04605575 Pyrotinib Plus Vinorelbine in Participants With HER2-positive Previously Treated Locally Advanced or Metastatic Breast Cancer Status UNKNOWN Phase PHASE2
NCT04602117 ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer Status WITHDRAWN Phase PHASE1
NCT04588545 Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04585750 The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) Status RECRUITING Phase PHASE1/PHASE2
NCT04582968 Pyrotinib Combined With Brain Radiotherapy in Breast Cancer Patients With Brain Metastases Status UNKNOWN Phase PHASE1/PHASE2
NCT04578106 Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy Status TERMINATED Phase PHASE2
NCT04569747 A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04512261 TOPAZ: Tucatinib in COmbination With Pembrolizumab And TrastuZumab in Patients With HER2-Positive Breast Cancer Brain Metastases Status WITHDRAWN Phase PHASE1/PHASE2
NCT04487236 Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid Tumors Status COMPLETED Phase PHASE1
NCT04481932 Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer Status RECRUITING Phase PHASE2
NCT04464967 Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers Status WITHDRAWN Phase PHASE1/PHASE2