NCT04588545 Radiation Therapy Followed by Intrathecal Trastuzumab/Pertuzumab in HER2+ Breast Leptomeningeal Disease Status ACTIVE_NOT_RECRUITING Phase PHASE1/PHASE2
NCT04585750 The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) Status RECRUITING Phase PHASE1/PHASE2
NCT04582968 Pyrotinib Combined With Brain Radiotherapy in Breast Cancer Patients With Brain Metastases Status UNKNOWN Phase PHASE1/PHASE2
NCT04578106 Omission of Surgery in Clinically Low-risk HER2positive Breast Cancer With High HER2 Addiction and a Complete Response Following Standard Anti-HER2-based Neoadjuvant Therapy Status TERMINATED Phase PHASE2
NCT04569747 A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04512261 TOPAZ: Tucatinib in COmbination With Pembrolizumab And TrastuZumab in Patients With HER2-Positive Breast Cancer Brain Metastases Status WITHDRAWN Phase PHASE1/PHASE2
NCT04487236 Trial of ZN-A-1041 Enteric Capsules in Patients With HER2-Positive Advanced Solid Tumors Status COMPLETED Phase PHASE1
NCT04481932 Trastuzumab Combined With Pyrrolidine and Chemotherapy for Locally HER2 Positive Breast Cancer Status RECRUITING Phase PHASE2
NCT04464967 Safety and Preliminary Efficacy of SNK01 in Combination With Trastuzumab or Cetuximab in Subjects With Advanced HER2 or EGFR Cancers Status WITHDRAWN Phase PHASE1/PHASE2
NCT04457700 CT-based Radiomics of ALN pCR (ypN0) in Breast Cancer Undergoing NAC Status UNKNOWN Phase N/A
NCT04450732 Safety of GQ1001 in Adult Patients With HER2-Positive Advanced Solid Tumors Status RECRUITING Phase PHASE1
NCT04420598 DS-8201a for trEatment of aBc, BRain Mets, And Her2[+] Disease Status COMPLETED Phase PHASE2
NCT04419181 Feasibility of Chemotherapy De-escalation in Early-Stage HER2 Positive Breast Cancer Status WITHDRAWN Phase PHASE2
NCT04395508 An Expanded Access Study to Provide at Home Subcutaneous Administration of Pertuzumab and Trastuzumab Fixed-Dose Combination (PH FDC SC) for Patients With HER2-Positive Breast Cancer During the COVID-19 Pandemic Status APPROVED_FOR_MARKETING Phase N/A
NCT04360941 PAveMenT: Palbociclib and Avelumab in Metastatic AR+ Triple Negative Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04337658 Anti-HER2 Therapy + Fulvestrant/Capecitabine in Women With HR+, HER2+, Non-visceral Metastases Stage IV Breast Cancer Status NOT_YET_RECRUITING Phase PHASE3
NCT04332588 Monitoring HER2+ Breast Cancer Neoadjuvant Treatment With Advanced PET/MRI Status RECRUITING Phase PHASE1
NCT04288141 A Study to Measure the Expression of the HER2-HER3 Dimer in Tumour and Blood (Exosomes) Samples From Patients With HER2 Positive Breast Cancer Receiving HER2 Targeted Therapies Status UNKNOWN Phase N/A
NCT04281641 Markers to Evaluate the Efficacy of PH-based Regimen as a Neoadjuvant Therapy for Operable HER2 Positive Breast Cancer Status RECRUITING Phase NA