The Pathways clinical trial into puberty blockers has been paused after the MHRA raised concerns about minimum age limits and unquantified long-term biological risks, with recruitment now suspended pending resolution.
The MHRA has raised new safety concerns about the PATHWAYS clinical trial investigating puberty blockers in young people with gender incongruence, pausing preliminary work until issues are resolved with sponsor King's College London.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07187947 |
Cardiovascular Health of Transgender Individuals During the Gender-affirming Pathway |
RECRUITING | |
| NCT07128771 |
Cardiomodulatory Effects of Gender-Affirming Hormone Therapy |
ENROLLING_BY_INVITATION | |
| NCT06953908 |
The Copenhagen Gender Identity Cohort |
RECRUITING | |
| NCT06774053 |
Swiss ProspectivE Cohort of TRAnsgender and Gender Diverse Individuals - The SPECTRA Study |
RECRUITING | |
| NCT06573177 |
Optimizing Individual Health Care for Young People With Gender Incongruence |
RECRUITING | |
| NCT06565663 |
MaPGAS Decision Making |
ENROLLING_BY_INVITATION | NA |
| NCT06530992 |
The Effect of Tucking on Semen Quality of Adult Trans Women |
RECRUITING | |
| NCT05925361 |
Peritoneum Vaginoplasty; Implementation According to IDEAL Framework |
UNKNOWN | NA |
| NCT05583058 |
Sex Hormone Overdose and Misuse in Chinese Transgender and Gender Non-conforming Population |
NOT_YET_RECRUITING | |
| NCT05318755 |
China Gender-affirming Hormone Therapy Study |
RECRUITING |
