Gastroparesis is a disorder of delayed gastric emptying in which the stomach slows or stops movement of food to the small intestine without mechanical obstruction. It can cause nausea, vomiting, bloating, early satiety, and nutritional complications. Common associations include diabetes and vagus-nerve injury after upper GI surgery.
New research links GLP-1 drugs like Ozempic to increased scurvy risk through appetite suppression and poor nutrition. University of Florida researchers are testing a GLP-1 implant for obese cats as feline obesity affects nearly 60% of US cats.
The FDA approved tradipitant (Nereus), an oral NK-1 receptor antagonist, for prevention of motion-induced vomiting on December 30, 2025. The approval marks the first new pharmacologic treatment for motion sickness in over four decades.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07556237 |
Gastric Electrical Stimulation for Abdominal Pain in Patients With Gastroparesis |
NOT_YET_RECRUITING | NA |
| NCT07526935 |
Combined Role of Gastric Peroral Endoscopic Myotomy and Gastric Electrical Stimulator |
ACTIVE_NOT_RECRUITING | NA |
| NCT07474415 |
Controlled Trial of Gastric Electrical Stimulation in Children |
COMPLETED | NA |
| NCT07360262 |
Gastric Emptying Recovery After GLP-1 RA Cessation |
COMPLETED | |
| NCT07104214 |
Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy |
RECRUITING | |
| NCT06991036 |
Validation of Plant-Based Vegan Meal for Gastric Emptying Testing in 10 Healthy Subjects |
COMPLETED | NA |
| NCT06965543 |
G-POEM for Glycemic Control in Diabetic Gastroparesis |
NOT_YET_RECRUITING | NA |
| NCT06854120 |
Prokinetics and Body Surface Gastric Mapping in Dyspeptic Patients: Baseline and Treatment Effects |
NOT_YET_RECRUITING | |
| NCT06836557 |
Open Label Safety Study of Tradipitant in Idiopathic and Diabetic Gastroparesis |
RECRUITING | PHASE3 |
| NCT06827548 |
ABVN Phase 2-Studying the Effect of Stimulation on the Auricular Branch of the Vagal Nerve -B |
COMPLETED | NA |
