News Related to Gastrointestinal Malignancies

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NovaBridge Enrolls First Patient in Phase 2 Study of Givastomig for Gastric Cancer

Feb 18, 2026

NovaBridge Biosciences has enrolled the first patient in a global Phase 2 study evaluating givastomig in combination with nivolumab and chemotherapy for HER2-negative, first-line metastatic gastric cancer, with top-line results expected in 2027.

TROP2-Targeted ADCs with Topoisomerase I Inhibitors Advance in Oncology

Nov 04, 2025

Antibody-drug conjugates targeting TROP2 with topoisomerase I inhibitor payloads are currently marketed in breast and lung cancer, with over 100 such ADCs now in clinical trials for various malignancies including gastrointestinal tumors.