Familial Amyotrophic Lateral Sclerosis

Disease

Also known as: familial ALS

Related News

Actor Eric Dane Dies of ALS at 53; NFL Star Chris Johnson Also Diagnosed

Actor Eric Dane died of ALS at age 53 in February 2026, less than a year after announcing his diagnosis. Former NFL star Chris Johnson also revealed his ALS diagnosis at age 39. The cases highlight the neurodegenerative disease, which affects about 33,000 people in the U.S. and has no cure.

Experimental ALS Therapies QRL-201 and Neflamapimod Advance in Clinical Trials

Two experimental ALS therapies showed promise in recent clinical developments. Interim Phase 1/2 data suggest the antisense oligonucleotide QRL-201 restores a critical nerve protein and may slow disease decline, with a Phase 3 trial planned for 2027. Meanwhile, the oral therapy neflamapimod has been selected for testing in the UK's EXPERTS-ALS platform study, with first results expected this spring.