News Related to End-Stage Organ Failure

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Review Charts Shift Toward Treg-Based Active Tolerance in Solid Organ Transplantation

May 12, 2026

A 2026 review outlines the shift in solid organ transplantation from broad immunosuppression to Treg-based active tolerance. It covers polyclonal Tregs, CAR-Tregs and CRISPR-edited off-the-shelf products.

Regulatory T Cell Therapies Advance for Autoimmune Diseases and Transplant Rejection

Feb 13, 2026

Engineered regulatory T cell therapies are progressing through clinical trials for autoimmune diseases and organ transplant rejection, with CAR-Treg candidates showing promising early results in rheumatoid arthritis and other conditions.