FDA Approves Shionogi's XOCOVA as First Oral Drug for COVID-19 Prevention After Exposure
Jun 01, 2026
The FDA has approved Shionogi's XOCOVA (ensitrelvir) as the first oral antiviral for post-exposure prophylaxis of COVID-19. Approval was based on the Phase 3 SCORPIO-PEP trial, which showed a 67% reduction in risk of symptomatic disease after exposure.