ALX Oncology has multiple 2026 catalysts for Evorpacept and ALX2004. Interim ASPEN-09 data are expected in Q3 2026, while an initial safety update from the phase 1 ALX2004 trial is expected in 1H 2026.
An experimental immunotherapy drug shows tumor shrinkage in prostate cancer patients, while Eli Lilly's selpercatinib reduces recurrence risk in early-stage lung cancer. A separate study reveals persistent racial disparities in curative treatment for lung cancer patients.
Grail's NHS-Galleri trial of 142,000 participants failed to achieve statistically significant reduction in late-stage cancer diagnoses, though secondary endpoints showed four-fold improvement in overall cancer detection rate. Stock fell 48% following the announcement.
New research warns AI pathology systems may use statistical shortcuts rather than biological signals, while a clinical trial shows stereotactic radiation improves quality of life for patients with multiple brain metastases compared to whole brain radiation.
Vir Biotechnology announced a global strategic collaboration with Astellas for VIR-5500, a PSMA-targeted dual-masked T-cell engager for prostate cancer, and reported $781.6 million in cash and investments as of December 31, 2025.
Oncolytics Biotech announced FDA Fast Track Designation for pelareorep combined with bevacizumab and FOLFIRI for second-line treatment of KRAS-mutant metastatic colorectal cancer, driving shares up 19.7%.
Immunotherapy is increasingly being used before and after surgery across seven cancer types, while the global immunotherapy drugs market experiences significant growth driven by advances in biotechnology and targeted therapies.
The FDA approved Optune Pax, a wearable Tumor Treating Fields device, for locally advanced pancreatic cancer in combination with gemcitabine and nab-paclitaxel. The approval marks the first new treatment for this indication in nearly 30 years.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07540845 |
Regular Diet After Colorectal Surgery |
RECRUITING | NA |
| NCT07431723 |
Creation of Compression Anastomosis Using the GT Metabolic Magnet System |
RECRUITING | NA |
| NCT07176715 |
Same-Day Colectomy: is it Safe for Patients? |
RECRUITING | NA |
| NCT06879912 |
A Study to Understand the Utility of the Force Feedback Instruments in Robotic Procedures Using da Vinci 5 Robot |
RECRUITING | |
| NCT06767046 |
KRAS-Specific Autologous TCR-T Cell Therapy for KRAS Mutation in Advanced Solid Tumors |
ACTIVE_NOT_RECRUITING | PHASE1 |
| NCT06065696 |
Enhanced Recovery After Surgery Protocol on Early Mobilization After Colorectal Surgery |
COMPLETED | |
| NCT05947838 |
A Prospective Feasibility Study Using ctDNA to Tailor Neoadjuvant Chemotherapy for Patients With Colorectal or Appendiceal Adenocarcinoma |
RECRUITING | NA |
| NCT05416866 |
Transversus Abdominis Plane Block Plus Quadratus Lumborum Block or Retrolaminar Block of Multiple Injections for Postoperative Analgesia Following Laparoscopic Colorectal Surgery |
UNKNOWN | PHASE4 |
| NCT04437615 |
Colorectal Polyp Clinical Decision Support Device Study |
COMPLETED | |
| NCT00582829 |
Colorectal Cancer Screening Intervention for Family Members of Colorectal Cancer Patients |
COMPLETED |
