New research links coffee to lower liver disease risk and sugary beverages to higher liver cancer risk. Two studies appear in Clinical Gastroenterology and Hepatology and JAMA Network Open.
A study from the University of Osaka identified the integrin αV–YAP–CTGF pathway linking chronic liver congestion to fibrosis. The findings point to a potential therapeutic target in congestion-related liver disease.
Research shows chloramine disinfection successfully stopped a Legionnaires' disease outbreak in Minnesota, while clinical data reveals Legionella pneumonia has 11.9% 30-day mortality and disproportionately affects immunocompromised patients. The studies highlight both prevention strategies and diagnostic challenges.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07703540 |
Inferior Vena Cava Pressure as Alternative to Hepatic Venous Pressure for EUS-guided Portal Pressure Gradient Measurement |
COMPLETED | |
| NCT07668778 |
Evaluation of a Modified Bowel Preparation Regimen in Cirrhotic Patients Undergoing Colonoscopy |
NOT_YET_RECRUITING | PHASE3 |
| NCT07652203 |
Impact of Propranolol on the Prognosis of Patients With Decompensated Cirrhosis and MELD Score > 9 |
NOT_YET_RECRUITING | NA |
| NCT07651683 |
Clinical Characteristics of Recompensation |
ACTIVE_NOT_RECRUITING | |
| NCT07647978 |
Development of a Predictive Score for the Risk of Infection in the Immediate Post-liver-transplant Period |
NOT_YET_RECRUITING | |
| NCT07634237 |
Personalized Nutritional Intervention in Patients Undergoing TIPS Insertion for Refractory Ascites to Prevent Overt Hepatic Encephalopathy |
NOT_YET_RECRUITING | NA |
| NCT07554183 |
4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in Cirrhosis |
NOT_YET_RECRUITING | NA |
| NCT07417163 |
LiverSleep: A Behavioral Sleep Intervention for Patients With Cirrhosis and Insomnia |
COMPLETED | NA |
| NCT07046429 |
Affect of Melatonin on Sleep and Cognition in Cirrhosis |
RECRUITING | NA |
| NCT07042919 |
Zanzalintinib in Second Line and Beyond for the Treatment of Advanced Liver Cancer |
RECRUITING | PHASE1/PHASE2 |
