FDA approves MannKind's Afrezza inhaled insulin for children aged 6+ with type 1 and type 2 diabetes. Separately, an updated label provides new starting dose guidance for adults switching from injections or insulin pumps.
The European Commission approved Enflonsia for prevention of RSV lower respiratory tract disease in infants during their first RSV season. Merck also reported new Phase 3 SMART data showing generally consistent second-season safety in high-risk children under 2 years old.
The World Health Organization has recommended new portable TB diagnostic tests that deliver results in under an hour, while researchers developed an inhalable nanoparticle treatment that could replace daily pills. TB remains the world's deadliest infectious disease, killing 1.2 million people in 2024 despite being preventable and curable.
Researchers have developed an inhalable nanoparticle system for delivering rifampin directly to the lungs, potentially reducing tuberculosis treatment from daily to once-weekly dosing while lowering side effects and improving drug effectiveness.
Merck announced positive second RSV season findings from the Phase 3 SMART trial evaluating ENFLONSIA (clesrovimab) in infants and children under 2 years at increased risk for severe RSV disease, showing consistent safety and antibody levels similar to healthy infants.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07364682 |
Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography |
NOT_YET_RECRUITING | |
| NCT07151768 |
Prospective Validation of the Novel PVD-B65 Risk Score in Patients With Chronic Lung Disease and Pulmonary Hypertension |
RECRUITING | |
| NCT07097961 |
Paediatric Post-TB Pulmonary Rehab Study |
RECRUITING | NA |
| NCT06870032 |
Pulmonary Rehabilitation and Quality of Life in Children With Chronic Lung Diseases: A Multidisciplinary Approach |
COMPLETED | NA |
| NCT06592235 |
Awareness of Individuals with Chronic Lung Disease About Climate Change, Heat Waves, Air Pollution and Physical Activity |
RECRUITING | |
| NCT06559670 |
Prevention of Chronic Lung Disease (CLD - Prevention Study) |
NOT_YET_RECRUITING | NA |
| NCT06545851 |
Effects of an Automatic Oxygen Titration System in People With Hypoxemia During Exercise Training |
RECRUITING | NA |
| NCT06514378 |
Safety of Endobronchial Mesenchymal Stromal Cells in the Treatment of Chronic Lung Allograft Dysfunction |
RECRUITING | PHASE1 |
| NCT06479252 |
Comparing Centre-based, Remotely Supervised, and Self-administered STS Tests in Individuals With CRD |
RECRUITING | NA |
| NCT06474767 |
Using Parent Engagement to Improve the Wellbeing of Black Premature Infants With Chronic Lung Disease |
NOT_YET_RECRUITING | NA |
