Also known as: gallstones
Cholelithiasis is the presence of gallstones in the gallbladder or biliary tract. It may be asymptomatic or cause biliary pain and complications such as cholecystitis or pancreatitis.
The FDA has announced plans to crack down on active pharmaceutical ingredients used in compounded GLP-1 drugs and warned about the risks of these products. The agency has cited counterfeit products, non-FDA-approved ingredients and more than 1,000 adverse event reports tied to compounded semaglutide and tirzepatide.
GLP-1 weight loss drugs show increasing efficacy but raise concerns about excessive weight loss, side effects, and the rise of unregulated compounded versions sold online.
A 30-year-old female with stage IV gallbladder adenocarcinoma achieved complete metabolic resolution of metastases after three cycles of pembrolizumab, gemcitabine, and cisplatin, despite presenting without traditional risk factors.
Clinical studies demonstrate GLP-1 receptor agonists like semaglutide and tirzepatide produce substantial weight loss when combined with lifestyle changes, with patients achieving mean reductions of 14.9% body weight over 68 weeks.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07595692 |
Tri-Radial Port Extension for Difficult Gallbladder Extraction |
COMPLETED | NA |
| NCT07552701 |
USG-Guided TAPA vs RIFB Block for Postoperative Analgesia in Laparoscopic Cholecystectomy |
RECRUITING | NA |
| NCT07512024 |
Effects of Postoperative Video-assisted Early Mobilization on Recovery Outcomes |
NOT_YET_RECRUITING | NA |
| NCT07490730 |
Antegrade Transcystic Balloon Dilatation of the Papillary Sphincter During Emergency Laparoscopic Cholecystectomy for Common Bile Duct Stones |
COMPLETED | |
| NCT07478601 |
Effect of Erector Spinae Plane Block on Postoperative Respiratory Function After Laparoscopic Cholecystectomy |
NOT_YET_RECRUITING | NA |
| NCT07473687 |
Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room |
RECRUITING | |
| NCT07465406 |
Postoperative Pain Will be Compared in Cholecystectomy Patients: Half Receiving TAP Block and Half Without it. |
COMPLETED | NA |
| NCT07452848 |
Impact of Pringle Maneuver on Postoperative Gallbladder Diseases After Hepatectomy |
RECRUITING | |
| NCT07388251 |
Effect of Intraperitoneal Dexmedetomidine Added to Bupivacaine 0.25% Versus Bupivacaine Alone on Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy |
COMPLETED | NA |
| NCT07363668 |
Investigation of the Effects of Aromatherapy Foot Massage on Postoperative Pain, Sleep, and Recovery in Laparoscopic Cholecystectomy |
COMPLETED | NA |
