NCT07053033 Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM) Status RECRUITING Phase PHASE2
NCT06992973 Efficacy of the Association of Fractionated SRS and Subsequent Surgery in Patients With Brain Metastases Status RECRUITING Phase NA
NCT06869460 Multicenter Retrospective Study on Patients Treated with Stereotactic Radiosurgery/Radiotherapy for Single Brain Lesions: Evaluation of Treatment Efficacy and Safety, Also Through Radiomic Analysis Methods. Status ACTIVE_NOT_RECRUITING Phase N/A
NCT06857006 Trial of Differential Margins in Single Isocenter Radiosurgery of Brain Metastases Status RECRUITING Phase NA
NCT06822543 A Single Arm, Phase 2 Study of Datopotamab Deruxtecan, Carboplatin, and Pembrolizumab for Treatment-naive Brain Metastases From NSCLC (Non-small Cell Lung Cancer) Status RECRUITING Phase PHASE2
NCT06793332 BrAin Metastasis in TripLe Negateive Breast Cancer: IvoneScimab and Trop2 ADC Status RECRUITING Phase PHASE2
NCT06728865 Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer with Brain Metastases: a Single-Arm, Open-Label, Prospective Phase II Clinical Study Status RECRUITING Phase PHASE2
NCT06712927 Trial of Relatlimab, Nivolumab, and Ipilimumab in Patients With Asymptomatic and Symptomatic Melanoma Brain Metastases Status RECRUITING Phase PHASE2
NCT06702826 Cadonilimab Combined With Stereotactic Radiotherapy as Second-line Treatment for Brain Metastases Status RECRUITING Phase PHASE2
NCT06649058 EXCLAIM: Exploring Combined Local and Systemic Approaches In Brain Metastasis: a Multi-cohort Randomized Phase II Study Evaluating Initial Response to Systemic Therapy and Subsequent Integration of Stereotactic Radiosurgery in Patients With Low-risk Brain Metastases and Central Nervous System-active Status RECRUITING Phase PHASE2
NCT06640582 TIL Therapy Combined With Pembrolizumab for Advanced Brain Cancer Including Gliomas and Meningiomas Status RECRUITING Phase PHASE1/PHASE2
NCT06620380 Ex Vivo Drug Response Evaluation for Next Generation Care of Brain Metastases Status RECRUITING Phase PHASE2
NCT06557187 Hippocampus-Avoidance Whole-Brain Radiation Therapy With Simultaneous Integrated Boost for BMs of NSCLC Status ACTIVE_NOT_RECRUITING Phase NA
NCT06511323 Evaluation of Brain Metastases Treated With Stereotactic Radiotherapy Using Dynamic [18F]FDG PET Status NOT_YET_RECRUITING Phase NA
NCT06501391 Cranial Radiotherapy Plus Chemoimmunotherapy in Untreated Driver-mutation Negative NSCLC With Stable Brain Metastasis Status RECRUITING Phase PHASE2
NCT06476093 SRT Combined With Anlotinib for the Treatment of Brain Metastases From Non-small Cell Lung Cancer Status RECRUITING Phase NA