Allergic rhinitis is an IgE-mediated inflammatory disease of the nasal mucosa triggered by environmental allergens, causing sneezing, rhinorrhea, nasal congestion, and itching.
Kymera Therapeutics presented Phase 1 data for oral STAT6 degrader KT-621 in healthy Japanese adults, showing ≥98% STAT6 degradation and favorable safety. Parallel Phase 2b trials in atopic dermatitis and asthma are ongoing with data expected in 2027, and FDA has granted Fast Track designation for both indications.
Needle-free allergy therapy is forecast to expand through 2035 as self-administered options gain share. House dust mite allergy treatment is projected to grow from $3.18 billion in 2025 to $8.75 billion by 2033.
Allergic rhinitis demonstrates both protective and risk associations with COVID-19 symptoms, while sublingual immunotherapy modifies respiratory and fever outcomes in patients with the condition.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07778537 |
AI-Guided Ultrasound Needling of Xinwu Point for Allergic Rhinitis |
COMPLETED | NA |
| NCT07651891 |
Evaluation of ALLERgen Specific Vaccination of DOG Allergic Patients in Swedish Practice |
RECRUITING | PHASE4 |
| NCT07620522 |
Observational Study of RHINOSEDAL in Acute Nasal Obstruction |
NOT_YET_RECRUITING | |
| NCT07588672 |
Evaluation of the Efficacy, Safety, and Tolerability of PL-14 Allergy Blocker Compared to Saline Spray in Patients With Seasonal Allergic Rhinitis |
NOT_YET_RECRUITING | NA |
| NCT07556393 |
Environmental Exposure Unit Trial in Subjects With Ragweed-induced Allergic Rhinitis |
COMPLETED | PHASE2 |
| NCT07453615 |
Effect of AI(Artificial Intelligence)-Based Storytelling Video on Anxiety and Fear During Skin Prick Test in Children |
COMPLETED | NA |
| NCT07435714 |
Facilitating Surgical Choice in Patient With Chronic Hypertrophic Rhinitis Using a Patient Decision Aid |
RECRUITING | NA |
| NCT07212530 |
EmoTIChealth: Promoting Adolescent Health Through a Serious Game. |
RECRUITING | NA |
| NCT07060885 |
A Research Study of House Dust Mite (HDM) SLIT-tablet for the Treatment of HDM Allergy in Chinese Participants Aged 12-65 |
ACTIVE_NOT_RECRUITING | PHASE3 |
| NCT06916884 |
Confirmatory Study on the Efficacy and Safety of the Fixed-dose Combination of Desloratadine/Betamethasone Versus Desloratadine |
COMPLETED | PHASE3 |
