Recent studies on metformin and age-related macular degeneration report conflicting findings: a JAMA Ophthalmology cohort found no association, while studies in Ophthalmology Retina and BMJ Open Ophthalmology found reduced odds of neovascular and intermediate AMD, respectively. All were observational.
Immune checkpoint inhibitors are associated with a significantly lower risk of non-neovascular age-related macular degeneration, while sociodemographic disparities strongly influence diabetic retinopathy screening adherence, according to two separate ophthalmology studies.
Axol Bioscience has acquired the ophthalmology business of Newcells Biotech, adding advanced retinal organoid and 2D RPE models to its iPSC portfolio. The deal follows Axol's acquisition of Phenocell and a $2.8 million financing led by BroadOak Capital Partners. Financial terms were not disclosed.
Zydus Lifesciences launched ANYRA, India's first indigenously developed aflibercept biosimilar, on February 19, 2026, following an agreement with Regeneron Pharmaceuticals and Bayer for multiple ophthalmic indications.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07496567 |
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-003) |
RECRUITING | PHASE2/PHASE3 |
| NCT07440225 |
A Clinical Trial of EYE201/MK-8748 in People With Macular Degeneration (MK-8748-002) |
RECRUITING | PHASE2/PHASE3 |
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RECRUITING | PHASE1/PHASE2 |
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ACTIVE_NOT_RECRUITING | PHASE4 |
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A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) |
TERMINATED | PHASE1 |
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Microcurrent Stimulation Therapy for Intermediate to Advanced Nonexudative Age-related Macular Degeneration |
RECRUITING | NA |
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RECRUITING | NA |
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Retinal Fundus Flavoprotein Fluorescence in Age Related Macular Degeneration |
COMPLETED | NA |
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Multicenter Real-life Observational Study Switched Aflibercept or Ranibizumab to Faricimab in Patients With AMD. |
RECRUITING | |
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Effects of Goji vs. Fiber on Macular Degeneration |
RECRUITING | NA |
