Also known as: stomach pain
Abdominal pain (stomach ache) is a symptom that can be associated with both minor and serious medical conditions. Because many vital organs lie in the abdomen, abdominal pain has a broad differential diagnosis and requires careful evaluation.
The FDA has announced plans to crack down on active pharmaceutical ingredients used in compounded GLP-1 drugs and warned about the risks of these products. The agency has cited counterfeit products, non-FDA-approved ingredients and more than 1,000 adverse event reports tied to compounded semaglutide and tirzepatide.
Over 25 companies are developing 30+ therapies for celiac disease, with recent positive trial results and FDA Fast Track designation. A new blood test using T-cell receptor sequencing may enable noninvasive diagnosis and monitoring.
The FDA approved Tecvayli plus Darzalex Faspro for relapsed/refractory multiple myeloma in March 2026, and Darzalex Faspro-based quadruplet D-VRd for newly diagnosed transplant-ineligible patients in January 2026.
A nationwide survey reveals 50% of Americans don't know colorectal cancer can be screened at home, as the disease becomes the leading cause of cancer death in adults under 50. Current guidelines recommend screening begin at age 45.
Actor James Van Der Beek died at age 48 from colorectal cancer, highlighting a troubling trend of rising cancer rates and deaths among younger Americans despite overall declines in older populations.
AbbVie announced positive topline results from the Phase 3 AFFIRM study showing risankizumab subcutaneous induction achieved superior clinical remission and endoscopic response rates versus placebo in adults with moderately to severely active Crohn's disease.
The FDA approved pembrolizumab in combination with paclitaxel, with or without bevacizumab, for adult patients with platinum-resistant epithelial ovarian, fallopian tube, or primary peritoneal carcinoma whose tumors express PD-L1 (CPS ≥1).
The FDA has expanded a recall of raw oysters from Stellar Bay Shellfish due to norovirus contamination and issued a nationwide recall of Tippy Toes baby food fruit puree due to elevated patulin levels.
Clinical studies demonstrate GLP-1 receptor agonists like semaglutide and tirzepatide produce substantial weight loss when combined with lifestyle changes, with patients achieving mean reductions of 14.9% body weight over 68 weeks.
The FDA announced plans to restrict non-FDA-approved compounded GLP-1 drugs mass-marketed as alternatives to approved weight loss medications, citing safety concerns and misleading advertising practices.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07591584 |
A Study Evaluating the Impact of Regular FODMAP-targeting Digestive Enzyme Blend Use on Gastrointestinal Symptoms in Individuals With Self-Reported Bloating |
RECRUITING | NA |
| NCT07535294 |
Assess Patient Readiness for Pelvic Ultrasound With the Use of Artificial Intelligence |
COMPLETED | NA |
| NCT07526727 |
ADAPTing CBT for Pediatric Functional Abdominal Pain in Primary Care |
NOT_YET_RECRUITING | NA |
| NCT07338643 |
The Auxiliary Effect of Artificial Intelligence in the Detection of Precancerous Lesions in Proximal Colon Cancer |
NOT_YET_RECRUITING | |
| NCT07155109 |
Different Intraperitoneal Pressures on Optic Nerve Sheath Diameter in Laparoscopic Surgeries |
NOT_YET_RECRUITING | NA |
| NCT06835504 |
Morphine or Ketamine for Analgesia |
NOT_YET_RECRUITING | PHASE3 |
| NCT06827730 |
PoCUS Impact on the Diagnostic Approach for Thoracic and Abdominal Pain in the ED |
RECRUITING | NA |
| NCT06686875 |
Chronic Abdominal Pain After Laparoscopic Sleeve Gastrectomy |
ENROLLING_BY_INVITATION | |
| NCT06659172 |
Effects of tVNS on Visceral Pain |
COMPLETED | NA |
| NCT06543316 |
Marginal Ulcer Healing With Low-Thermal Argon Plasma Endoscopic Treatment |
RECRUITING | NA |
