Also known as: stomach pain
Abdominal pain (stomach ache) is a symptom that can be associated with both minor and serious medical conditions. Because many vital organs lie in the abdomen, abdominal pain has a broad differential diagnosis and requires careful evaluation.
The UK MHRA approved oral semaglutide (Wegovy) as the first GLP-1 weight loss tablet on 11 June 2026. A new report links high-dose tirzepatide to anhedonia, and data show bariatric surgery declining sharply as GLP-1 use surges.
FDA approved Novartis' Fabhalta for IgAN to slow kidney function decline. Phase III ALIGN data for Vanrafia showed ~34% slower eGFR decline vs placebo and were published in The Lancet.
FDA granted traditional approval to Novartis' Fabhalta (iptacopan) for IgA nephropathy. Phase 3 APPLAUSE-IgAN data showed eGFR decline slowed by 48% versus placebo over two years.
FDA approved zenocutuzumab-zbco (Bizengri) for NRG1 fusion-positive cholangiocarcinoma on May 8, 2026. The eNRGy trial showed a 36.8% ORR. It also received priority review, breakthrough, and orphan designations.
The FDA has announced plans to crack down on active pharmaceutical ingredients used in compounded GLP-1 drugs and warned about the risks of these products. The agency has cited counterfeit products, non-FDA-approved ingredients and more than 1,000 adverse event reports tied to compounded semaglutide and tirzepatide.
Over 25 companies are developing 30+ therapies for celiac disease, with recent positive trial results and FDA Fast Track designation. A new blood test using T-cell receptor sequencing may enable noninvasive diagnosis and monitoring.
The FDA approved Tecvayli plus Darzalex Faspro for relapsed/refractory multiple myeloma in March 2026, and Darzalex Faspro-based quadruplet D-VRd for newly diagnosed transplant-ineligible patients in January 2026.
A nationwide survey reveals 50% of Americans don't know colorectal cancer can be screened at home, as the disease becomes the leading cause of cancer death in adults under 50. Current guidelines recommend screening begin at age 45.
Actor James Van Der Beek died at age 48 from colorectal cancer, highlighting a troubling trend of rising cancer rates and deaths among younger Americans despite overall declines in older populations.
AbbVie announced positive topline results from the Phase 3 AFFIRM study showing risankizumab subcutaneous induction achieved superior clinical remission and endoscopic response rates versus placebo in adults with moderately to severely active Crohn's disease.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07761156 |
Effect of Chewing Exercises and Abdominal Massage |
COMPLETED | NA |
| NCT07738744 |
A Clinical Trial to Evaluate the Effects of a Supplement on Symptoms Associated With Liver and Digestive Health |
COMPLETED | NA |
| NCT07676136 |
A Pilot Study Using Gut-Directed Hypnotherapy for Hospitalized Patients |
NOT_YET_RECRUITING | NA |
| NCT07649720 |
NaviCam Patency Capsule to Verify Gastrointestinal Patency |
NOT_YET_RECRUITING | NA |
| NCT07643142 |
Diagnostic Performance of Serum Calprotectin in Acute Appendicitis |
COMPLETED | |
| NCT07591584 |
A Study Evaluating the Impact of Regular FODMAP-targeting Digestive Enzyme Blend Use on Gastrointestinal Symptoms in Individuals With Self-Reported Bloating |
RECRUITING | NA |
| NCT07535294 |
Assess Patient Readiness for Pelvic Ultrasound With the Use of Artificial Intelligence |
COMPLETED | NA |
| NCT07526727 |
ADAPTing CBT for Pediatric Functional Abdominal Pain in Primary Care |
NOT_YET_RECRUITING | NA |
| NCT07338643 |
The Auxiliary Effect of Artificial Intelligence in the Detection of Precancerous Lesions in Proximal Colon Cancer |
NOT_YET_RECRUITING | |
| NCT07155109 |
Different Intraperitoneal Pressures on Optic Nerve Sheath Diameter in Laparoscopic Surgeries |
NOT_YET_RECRUITING | NA |
