A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of VX-661 in Combination With Ivacaftor
- Status
- COMPLETED
- Phase
- PHASE3
Clinical Trials Related to Vertex Pharmaceuticals Incorporated
Related studies linked through entity extraction aliases.
Clearing Lungs With Epithelial Sodium Channel (ENaC) Inhibition in Cystic Fibrosis (CF)
- Status
- COMPLETED
- Phase
- PHASE2
Energy Balance and Weight Gain With Ivacaftor Treatment
- Status
- COMPLETED
- Phase
- N/A
Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion
- Status
- COMPLETED
- Phase
- PHASE2
An Open-Label, Phase 1 Study in Healthy Adult Subjects to Examine the Effects of Multiple-Dose Ciprofloxacin on Ivacaftor and VX-661 in Combination With Ivacaftor
- Status
- COMPLETED
- Phase
- PHASE1
Open-Label Safety Study of Telaprevir and Sofosbuvir in Chronic Hepatitis C Genotype 1
- Status
- COMPLETED
- Phase
- PHASE2
Roll-Over Study of Ivacaftor in Cystic Fibrosis Pediatric Subjects With a CF Transmembrane Conductance Regulator Gene (CFTR) Gating Mutation
- Status
- COMPLETED
- Phase
- PHASE3
A Phase 3 Rollover Study of Lumacaftor in Combination With Ivacaftor in Subjects 12 Years and Older With Cystic Fibrosis
- Status
- COMPLETED
- Phase
- PHASE3
Phase 1, QT/QTC Interval Study in Healthy Subjects
- Status
- COMPLETED
- Phase
- PHASE1
A Phase 1 Study to Investigate the Food Effect of Lumacaftor in Combination With Ivacaftor
- Status
- COMPLETED
- Phase
- PHASE1
Study of Lumacaftor in Combination With Ivacaftor in Subjects 6 Through 11 Years of Age With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation
- Status
- COMPLETED
- Phase
- PHASE3
Vitamin D + Telaprevir + Peginterferon + Ribavirin for of Hepatitis C Genotype 1
- Status
- WITHDRAWN
- Phase
- PHASE2/PHASE3
Study of Lumacaftor in Combination With Ivacaftor in Subjects With Moderate Hepatic Impairment and Healthy Subjects
- Status
- COMPLETED
- Phase
- PHASE1
Phase 1 PK Interaction Study Between VX-509 and Prednisone or Methylprednisolone in Healthy Male Subjects
- Status
- COMPLETED
- Phase
- PHASE1
An Ocular Safety Study of Ivacaftor-Treated Pediatric Patients 11 Years of Age or Younger With Cystic Fibrosis
- Status
- COMPLETED
- Phase
- N/A
A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics, and Pharmacodynamics of VX-135 and Daclatasvir in Subjects With Genotype 1 Chronic Hepatitis C Chronic Hepatitis C
- Status
- COMPLETED
- Phase
- PHASE2
A Phase 2/3 Open-label Extension Study to Evaluate Long-Term Safety and Efficacy With VX-509 in Subjects With Rheumatoid Arthritis
- Status
- COMPLETED
- Phase
- PHASE2/PHASE3
Telaprevir Plus Standard of Care (SOC) in HCV Associated Hepatocellular Carcinoma (HCC)
- Status
- TERMINATED
- Phase
- PHASE3
A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation
- Status
- COMPLETED
- Phase
- PHASE3
A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation
- Status
- COMPLETED
- Phase
- PHASE3