Researchers at the University of Bath reported a bacterial system for producing, stapling, and testing millions of peptide molecules inside living cells. The Cell Chemical Biology study uses a survival-based assay to identify stable, functional peptide candidates.
Researchers at the University of Bath have developed a bacterial system that produces, chemically stabilizes, and tests millions of peptide drug candidates inside living cells, identifying inhibitors of transcription factor CREB1 overactive in multiple cancers.
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