News Related to Society of Gynecologic Oncology

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Relacorilant-nab-paclitaxel Improves Survival in Ovarian Cancer Despite Prior Taxane Use

May 30, 2026

The phase 3 ROSELLA trial showed relacorilant plus nab-paclitaxel significantly improved overall survival in platinum-resistant ovarian cancer by 4.1 months versus nab-paclitaxel alone. The benefit was consistent across all subgroups regardless of prior taxane exposure, leading to FDA approval in March 2026. The combination also met its progression-free survival endpoint and demonstrated a favorable safety profile.