A breakthrough ovarian cancer drug, mirvetuximab soravtansine, is now available on the NHS, offering extended survival and improved quality of life. The 'biological missile' therapy targets cancer cells directly, reducing side-effects compared to standard chemotherapy. Up to 400 patients in England could benefit each year.
Advances in precision mental health research include TMS findings published in Nature Molecular Psychiatry showing targeted brain stimulation can address specific depression and anxiety symptoms, the launch of the three-year GlobalMinds NHS genomic study analyzing 49,000 DNA samples, and the new $1 million Wellcome Prize for Mental Health Science.
The Pathways clinical trial into puberty blockers has been paused after the MHRA raised concerns about minimum age limits and unquantified long-term biological risks, with recruitment now suspended pending resolution.
Private prescriptions for GLP-1 weight-loss drugs in England are concentrated in affluent areas despite higher obesity rates in deprived regions. Online pharmacies face scrutiny for inadequate verification checks when dispensing these medications.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07054047 |
Improving Diagnosis and Treatment for Patients With Rectal Cancer |
NOT_YET_RECRUITING | NA |
| NCT06923943 |
Predicting Nurse Staffing Requirements From Routinely Collected Data |
ACTIVE_NOT_RECRUITING | |
| NCT06560931 |
Defining, Recognising and Escalating Maternal Early Deterioration (DREaMED) |
ACTIVE_NOT_RECRUITING | |
| NCT05993260 |
Using Text Messages to Boost COVID-19 Vaccine Booking Rate |
COMPLETED | NA |
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Behavioural Science Messages in Breast Cancer Screening |
COMPLETED | NA |
| NCT03979222 |
Observational Cohort Study of a National Extracorporeal Membrane Oxygenation Service for Adults With Respiratory Failure: the NHS ECMO Study. |
COMPLETED | |
| NCT03253757 |
PrEP Impact Trial: A Pragmatic Health Technology Assessment of PrEP and Implementation |
UNKNOWN |
