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NCT06386263 HER-TEMPO - Real World Treatment-related Outcomes on T-DXd in Canada Status COMPLETED Phase N/A
NCT06362252 A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03) Status RECRUITING Phase PHASE1/PHASE2
NCT06357533 Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations Status RECRUITING Phase PHASE3
NCT06350097 Phase III, Open-label Study of First-line Osimertinib With or Without Datopotamab Deruxtecan for EGFRm Locally Advanced or Metastatic Non-small Cell Lung Cancer Status RECRUITING Phase PHASE3
NCT06330064 A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) Status RECRUITING Phase PHASE1/PHASE2
NCT06298084 Dose-Expansion Modular Study To Explore the Safety, Tolerability, and Anti-tumor Activity of HER3- DXd Monotherapy and Combinations in Patients With Inoperable Advanced Breast Cancer (ABC) After Progression on T-DXd Status RECRUITING Phase PHASE1/PHASE2
NCT06279728 Medical Access Program for Datopotamab Deruxtecan in EGFRm NSCLC Patients Status APPROVED_FOR_MARKETING Phase N/A
NCT06262438 CHIP-AML22/Quizartinib: Quizartinib + Chemotherapy in Newly Diagnosed Pediatric FLT3-ITD+ and NPM1wt AML Patients Status RECRUITING Phase PHASE2
NCT06244485 A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT06222489 Whole Body HER3 Quantification With Radiolabelled Patritumab Deruxtecan (HER3-DXd) PET/CT Status RECRUITING Phase PHASE2
NCT06210776 A Study to Assess the Effectiveness of Trastuzumab Deruxtecan in Chinese Breast Cancer Patients (REFRESH) Status RECRUITING Phase N/A
NCT06203210 A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer Status RECRUITING Phase PHASE3
NCT06176261 DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs Status RECRUITING Phase PHASE2
NCT06174987 A Study to Provide Continued Access to and Assess Long-Term Safety of the Study Drug(s) Status RECRUITING Phase PHASE3
NCT06172478 A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors Status RECRUITING Phase PHASE2
NCT06161025 A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Status RECRUITING Phase PHASE2/PHASE3
NCT06112379 A Phase III Randomised Study to Evaluate Dato-DXd and Durvalumab for Neoadjuvant/Adjuvant Treatment of Triple-Negative or Hormone Receptor-low/HER2-negative Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT06110949 Thromboembolic Risk Assessment in Patients Admitted With Acute Medical Diseases to Conventional and At Home Hospitalization Status RECRUITING Phase N/A
NCT06103864 A Phase III Study of Dato-DXd With or Without Durvalumab Compared With Investigator's Choice of Chemotherapy in Combination With Pembrolizumab in Patients With PD-L1 Positive Locally Recurrent Inoperable or Metastatic Triple-negative Breast Cancer (TROPION-Breast05) Status RECRUITING Phase PHASE3