NCT05875168 First-in-Human Study of DS-3939a in Participants With Advanced Solid Tumors Status RECRUITING Phase PHASE1/PHASE2
NCT05866432 Phase II Study of Dato-DXd in Triple-negative Breast Cancer Patients With Newly Diagnosed or Progressing Brain Metastases Status RECRUITING Phase PHASE2
NCT05865990 HER3-DXd in Breast Cancer and NSCLC Brain Metastases and Solid Tumor Leptomeningeal Disease Status COMPLETED Phase PHASE2
NCT05804747 A Study to Evaluate Effectiveness and Safety of Edoxaban in Patients 80 Years of Age or Older With Nonvalvular Atrial Fibrillation Status COMPLETED Phase N/A
NCT05769764 A Study of Prevalence of HER3 Expression in Non-Small Cell Lung Cancer Status COMPLETED Phase N/A
NCT05769751 A Study to Describe the Real-world Treatment Patterns and Associated Outcomes in Patients of China With HER2-positive Unresectable or Metastatic Breast Cancer Status COMPLETED Phase N/A
NCT05765851 A Study of DS-1103a Combination Therapy in Participants With Advanced Solid Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT05683171 A Phase 1/2, Open-label Study of Valemetostat in Combination With Rituximab and Lenalidomide in Relapsed or Refractory Follicular Lymphoma Status RECRUITING Phase PHASE1/PHASE2
NCT05638802 A Study of DS-7011a in Patients With Systemic Lupus Erythematosus Status COMPLETED Phase PHASE1/PHASE2
NCT05633979 Phase 1b Study of EZH1/2 Inhibitor Valemetostat in Combination With Trastuzumab Deruxtecan in Subjects With HER2 Low/Ultra-low/Null Metastatic Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT05629585 A Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05620914 A Window of Opportunity Study of Patritumab Deruxtecan in Patients With Brain Metastases Status WITHDRAWN Phase PHASE2
NCT05583669 A Study to Assess the Safety and Pharmacokinetics of Multiple Ascending Subcutaneous Doses of DS-2325a in Healthy Subjects Status COMPLETED Phase PHASE1
NCT05573893 PROVIDENCE - Prospective Non-interventional Study (NIS) to Examine Patient-reported Outcomes and Real-world Clinical Data in Patients With HER2-positive, HER2-low or HER2-ultralow Unresectable or Metastatic Breast Cancer Treated With Trastuzumab Deruxtecan Status RECRUITING Phase N/A
NCT05569811 NeoadjuVAnt muLti-agENT Chemotherapy or Patritumab Deruxtecan With or Without endocrINE Therapy for High-risk HR+/HER2- Breast Cancer - VALENTINE Trial Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT05569252 A Study of DS-1211b in Individuals With PseudoXanthoma Elasticum Status COMPLETED Phase PHASE2
NCT05555732 Datopotamab Deruxtecan (Dato-DXd) and Pembrolizumab With or Without Platinum Chemotherapy in 1L Non-Small Cell Lung Cancer (TROPION-Lung07) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT05489211 Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03) Status RECRUITING Phase PHASE2