NCT05025722 Pseudoxanthoma Elasticum (PXE) Natural History Biomarkers in PXE Individuals and Their Biological Non-PXE Siblings Status COMPLETED Phase N/A
NCT04965766 Patritumab Deruxtecan (U3-1402) in Unresectable Locally Advanced or Metastatic Breast Cancer Status RECRUITING Phase PHASE2
NCT04940325 Datopotamab Deruxtecan (Dato-DXd, DS-1062a) in Advanced and/or Unresectable Non-Small Cell Lung Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04938817 Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98) Status RECRUITING Phase PHASE1/PHASE2
NCT04842877 Study of Valemetostat Tosylate as a Single Agent in Patients With Relapse/Refractory B-cell Lymphoma Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04807595 Estimation of the Prevalence of HER2 Low and Describe the SoC, Treatment Patterns, and Outcome in Real-world Practice Among Unresectable and/or Metastatic Breast Cancer Patients With HER2 Low Status Status COMPLETED Phase N/A
NCT04796831 A Study to Determine the Absolute Oral Bioavailability of Quizartinib Using a Radiolabeled Microtracer in Healthy Subjects Status COMPLETED Phase PHASE1
NCT04784715 Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04752059 Phase II Study of T-DX in HER2-positive Breast Cancer Brain Metastases Status COMPLETED Phase PHASE2
NCT04747496 Real-world Study on Edoxaban Treatment for Patients With Non-valvular Atrial Fibrillation in China Status COMPLETED Phase N/A
NCT04744831 Trastuzumab Deruxtecan in Participants With HER2-overexpressing Advanced or Metastatic Colorectal Cancer Status COMPLETED Phase PHASE2
NCT04739761 A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04707248 A Study of DS-6000a in Subjects With Advanced Renal Cell Carcinoma and Ovarian Tumors Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04704934 Trastuzumab Deruxtecan for Subjects With HER2-Positive Gastric Cancer or Gastro-Esophageal Junction Adenocarcinoma After Progression on or After a Trastuzumab-Containing Regimen (DESTINY-Gastric04) Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04703192 Valemetostat Tosylate (DS-3201b), an Enhancer of Zeste Homolog (EZH) 1/2 Dual Inhibitor, for Relapsed/Refractory Peripheral T-Cell Lymphoma (VALENTINE-PTCL01) Status ACTIVE_NOT_RECRUITING Phase PHASE2
NCT04699630 A Study of U3-1402 (Patritumab Deruxtecan) in Subjects With Metastatic Breast Cancer Status COMPLETED Phase PHASE2
NCT04686305 Phase Ib Study of the Safety of T-DXd and Immunotherapy Agents With and Without Chemotherapy in Advanced or Metastatic HER2+, Non-squamous NSCLC Status RECRUITING Phase PHASE1
NCT04676477 HER3-DXd (Patritumab Deruxtecan; U3-1402) in Combination With Osimertinib in Subjects With Locally Advanced or Metastatic EGFR-mutated Non-Small Cell Lung Cancer Status ACTIVE_NOT_RECRUITING Phase PHASE1
NCT04656652 Study of DS-1062a Versus Docetaxel in Previously Treated Advanced or Metastatic Non-small Cell Lung Cancer With or Without Actionable Genomic Alterations (TROPION-LUNG01) Status ACTIVE_NOT_RECRUITING Phase PHASE3