Cocrystal Pharma advanced CDI-988 in a Phase 1b norovirus study and received FDA Fast Track designation. Nuvation Bio reported $18.5 million in IBTROZI net product revenues and presented updated TRUST trial data. Nautilus Biotechnology progressed its proteomics platform toward commercialization, maintaining a cash runway through 2027.
A clinical study explores whether echocardiography can detect heart amyloid as an early sign of Alzheimer’s, while laboratory research maps a biphasic gene expression cascade in the brain that identifies new therapeutic targets.
Two recent studies advance Alzheimer's research: one finds combining anti-amyloid antibodies with natural compounds improves efficacy and safety, while another maps a molecular cascade that could reveal new therapeutic targets. The combination therapy study used aducanumab, lecanemab, resveratrol, and curcumin. The molecular study identified gene expression networks and proposed a two-stage disease model.
Three new CRISPR-based therapies show promise for treating heart failure through mitochondrial enhancement, cystic fibrosis via lipid nanoparticle gene insertion, and elevated cholesterol with single-dose gene editing targeting ANGPTL3.
| NCT ID | Title | Status | Phase |
|---|---|---|---|
| NCT07778823 |
Augmented Reality-Cardiopulmonary Resuscitation Support for Pediatric Resuscitation |
RECRUITING | NA |
| NCT07758114 |
Prenatal Education on Environmental Exposures During Pregnancy Study (PEEPS) |
RECRUITING | NA |
| NCT07744217 |
Identifying Biomarkers of Gastro Intestinal Comorbidities in Autism Spectrum Disorder |
COMPLETED | |
| NCT07730125 |
Gene-edited T Regulatory Cells (CRG-150) for the Treatment of Relapsed/Refractory Malignancies |
NOT_YET_RECRUITING | PHASE1/PHASE2 |
| NCT07729397 |
Autologous IC-Nine, CD30 CAR, and Constitutive IL7R Expressing EBVST for CD30 Lymphoma (ANCILE-30) |
NOT_YET_RECRUITING | PHASE1 |
| NCT07723937 |
GelPOINT® Path-Assisted Endoscopic Removal of Colon and Rectal Polyps: A Feasibility and Safety Study |
RECRUITING | |
| NCT07719088 |
Psilocybin Effects on Healthy Aging Biomarkers and Purpose in Life |
NOT_YET_RECRUITING | PHASE1 |
| NCT07674628 |
SALUD-M: Acceptance Based Coping Skills for Hispanic/Latinx Military Patients With Type 2 Diabetes |
RECRUITING | NA |
| NCT07672418 |
Postoperative Pain After Pediatric Adenotonsillectomy With Ketorolac or Ibuprofen |
NOT_YET_RECRUITING | |
| NCT07544979 |
Creation of a Decision Aid for Coronary Anomalies |
RECRUITING | NA |
