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NCT04201418 A Multicenter Observational Study to Evaluate the Effectiveness of Patisiran in Patients With Polyneuropathy of ATTRv Amyloidosis With a V122I or T60A Mutation Status COMPLETED Phase N/A
NCT04153149 HELIOS-B: A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy Status ACTIVE_NOT_RECRUITING Phase PHASE3
NCT04152200 A Study to Evaluate Lumasiran in Patients With Advanced Primary Hyperoxaluria Type 1 Status COMPLETED Phase PHASE3
NCT04125472 Expanded Access Protocol to Provide Lumasiran to Patients With Primary Hyperoxaluria Type 1 Status APPROVED_FOR_MARKETING Phase N/A
NCT04056481 Expanded Access Protocol of Givosiran for Patients With Acute Hepatic Porphyria Status APPROVED_FOR_MARKETING Phase N/A
NCT03997383 APOLLO-B: A Study to Evaluate Patisiran in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy) Status COMPLETED Phase PHASE3
NCT03934307 A Study to Evaluate ALN-AGT01 in Patients With Hypertension Status COMPLETED Phase PHASE1
NCT03905694 A Study of Lumasiran in Infants and Young Children With Primary Hyperoxaluria Type 1 Status COMPLETED Phase PHASE3
NCT03862807 Patisiran in Patients With Hereditary Transthyretin-mediated Amyloidosis (hATTR Amyloidosis) Disease Progression Post-Liver Transplant Status COMPLETED Phase PHASE3
NCT03841448 A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN) Status TERMINATED Phase PHASE2
NCT03774784 A Study of the Natural History of Leukocyte Chemotactic Factor 2 Amyloidosis (ALECT2) Disease Status TERMINATED Phase N/A
NCT03767829 A Study of ALN-AAT02 in Healthy Participants and Participants With ZZ Type Alpha-1 Antitrypsin Deficiency Liver Disease Status TERMINATED Phase PHASE1/PHASE2
NCT03759379 HELIOS-A: A Study of Vutrisiran (ALN-TTRSC02) in Patients With Hereditary Transthyretin Amyloidosis (hATTR Amyloidosis) Status COMPLETED Phase PHASE3
NCT03681184 A Study to Evaluate Lumasiran in Children and Adults With Primary Hyperoxaluria Type 1 Status COMPLETED Phase PHASE3
NCT03672188 Study of VIR-2218 in Healthy Subjects and Patients With Chronic Hepatitis B Status COMPLETED Phase PHASE1/PHASE2
NCT03547297 INSIGHT-AHP: A Study to Characterize the Prevalence of Acute Hepatic Porphyria (AHP) in Patients With Clinical Presentation and History Consistent With AHP Status TERMINATED Phase N/A
NCT03505853 A Study to Investigate the Interaction Between Givosiran and a 5-probe Drug Cocktail in Patients With Acute Intermittent Porphyria (AIP) Status COMPLETED Phase PHASE1
NCT03350451 An Extension Study of an Investigational Drug, Lumasiran (ALN-GO1), in Participants With Primary Hyperoxaluria Type 1 Status COMPLETED Phase PHASE2